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- W2320807894 abstract "Background: High frequency deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an effective surgical treatment for Parkinson's Disease (PD) improving all cardinal motor symptoms by affecting striato-thalamic pathways to motor cortices. The STN is also known to be interconnected with limbic and prefrontal associative areas. Clinical observations of STN-DBS reported emotional effects like acute depression, acute episodes of laughter, relief from depression as well as changes in executive and memory functions. These findings have been characterised by analysis of stimulation pole localisation and functional PET imaging. However, pathological crying (PLC)- a phenomenon of incontinence of affect – induced by DBS has never been reported so far. A recent theory suggests that PLC is caused by a disruption of higher association areas (that are involved in the adjustment of emotional responses according to a specific social context) from the cerebellum which computes profiles of emotional responses." @default.
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- W2320807894 date "2004-01-01" @default.
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- W2320807894 title "Pathological crying induced by deep brain stimulation" @default.
- W2320807894 doi "https://doi.org/10.1055/s-2004-833147" @default.
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