Matches in SemOpenAlex for { <https://semopenalex.org/work/W2320850749> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2320850749 abstract "Objective To study the effects and mechanism of Hedysarum Polybotys Saccharide (HPS) on ventricular remodeling induced by isoprenaline (ISO) in the mouse. Methods Ventricular remodeling model was induced by subcutaneous injections of ISO for continuous fourteen days. Mice were randomly divided into control group, ISO group, low-dose group, middle-dose group and high-dose group of HPS were introduced by intergalactic (fig.) administration for twenty one days.Cardiac mass index of mouse was calculated at the end of experiment, hydroxyproline (Hyp) content, nitric oxide (NO) content, nitric oxide synthase (NOS) activity, superoxide dismutase (SOD) activity and malondialdehyde (MDA) content in myocardial tissue were measured by spectrophotometry. Results Compared with control group, the heart weight index and Hyp content in ISO group was significantly increased (p<0.01), the SOD activity was decreased (p<0.01) and MDA content was increased (p<0.01), the NOS activity and NO level were reduced (p<0.05, p<0.01). Compared with the ISO group, HPS group could reduce the heart weight index obviously (p<0.05), inhibited the Hyp content, increased SOD activity and reduced MDA content, enhanced NOS activity and NO level in myocardium (p<0.05 and p<0.01). Conclusion HPS have inhibitory effects on ventricular remodeling induced by ISO in mice. Its mechanisms may be related to increasing NOS activity and NO level, in addition to enhancing the antioxidant ability of heart." @default.
- W2320850749 created "2016-06-24" @default.
- W2320850749 creator A5001659745 @default.
- W2320850749 creator A5011674133 @default.
- W2320850749 creator A5028133176 @default.
- W2320850749 creator A5061899351 @default.
- W2320850749 creator A5090815103 @default.
- W2320850749 date "2016-01-01" @default.
- W2320850749 modified "2023-09-27" @default.
- W2320850749 title "Evaluation of Effects and Mechanism of Hedysarum Polybotys Saccharide on Ventricular Remodeling in Mice Model" @default.
- W2320850749 cites W2089728326 @default.
- W2320850749 cites W2100945682 @default.
- W2320850749 cites W2131523926 @default.
- W2320850749 doi "https://doi.org/10.2991/icmmct-16.2016.78" @default.
- W2320850749 hasPublicationYear "2016" @default.
- W2320850749 type Work @default.
- W2320850749 sameAs 2320850749 @default.
- W2320850749 citedByCount "0" @default.
- W2320850749 crossrefType "proceedings-article" @default.
- W2320850749 hasAuthorship W2320850749A5001659745 @default.
- W2320850749 hasAuthorship W2320850749A5011674133 @default.
- W2320850749 hasAuthorship W2320850749A5028133176 @default.
- W2320850749 hasAuthorship W2320850749A5061899351 @default.
- W2320850749 hasAuthorship W2320850749A5090815103 @default.
- W2320850749 hasBestOaLocation W23208507491 @default.
- W2320850749 hasConcept C126322002 @default.
- W2320850749 hasConcept C134018914 @default.
- W2320850749 hasConcept C185592680 @default.
- W2320850749 hasConcept C24998067 @default.
- W2320850749 hasConcept C2775838275 @default.
- W2320850749 hasConcept C2776090920 @default.
- W2320850749 hasConcept C2777622882 @default.
- W2320850749 hasConcept C2778004101 @default.
- W2320850749 hasConcept C2778198053 @default.
- W2320850749 hasConcept C2778248901 @default.
- W2320850749 hasConcept C2778401633 @default.
- W2320850749 hasConcept C2779537366 @default.
- W2320850749 hasConcept C2779797417 @default.
- W2320850749 hasConcept C519581460 @default.
- W2320850749 hasConcept C55493867 @default.
- W2320850749 hasConcept C71924100 @default.
- W2320850749 hasConceptScore W2320850749C126322002 @default.
- W2320850749 hasConceptScore W2320850749C134018914 @default.
- W2320850749 hasConceptScore W2320850749C185592680 @default.
- W2320850749 hasConceptScore W2320850749C24998067 @default.
- W2320850749 hasConceptScore W2320850749C2775838275 @default.
- W2320850749 hasConceptScore W2320850749C2776090920 @default.
- W2320850749 hasConceptScore W2320850749C2777622882 @default.
- W2320850749 hasConceptScore W2320850749C2778004101 @default.
- W2320850749 hasConceptScore W2320850749C2778198053 @default.
- W2320850749 hasConceptScore W2320850749C2778248901 @default.
- W2320850749 hasConceptScore W2320850749C2778401633 @default.
- W2320850749 hasConceptScore W2320850749C2779537366 @default.
- W2320850749 hasConceptScore W2320850749C2779797417 @default.
- W2320850749 hasConceptScore W2320850749C519581460 @default.
- W2320850749 hasConceptScore W2320850749C55493867 @default.
- W2320850749 hasConceptScore W2320850749C71924100 @default.
- W2320850749 hasLocation W23208507491 @default.
- W2320850749 hasOpenAccess W2320850749 @default.
- W2320850749 hasPrimaryLocation W23208507491 @default.
- W2320850749 hasRelatedWork W141599729 @default.
- W2320850749 hasRelatedWork W165915388 @default.
- W2320850749 hasRelatedWork W2315068378 @default.
- W2320850749 hasRelatedWork W2347827735 @default.
- W2320850749 hasRelatedWork W2358723993 @default.
- W2320850749 hasRelatedWork W2365271218 @default.
- W2320850749 hasRelatedWork W2381927449 @default.
- W2320850749 hasRelatedWork W2394964900 @default.
- W2320850749 hasRelatedWork W2397616464 @default.
- W2320850749 hasRelatedWork W2401747684 @default.
- W2320850749 hasRelatedWork W2643793917 @default.
- W2320850749 hasRelatedWork W2911408519 @default.
- W2320850749 hasRelatedWork W3024238426 @default.
- W2320850749 hasRelatedWork W3029493031 @default.
- W2320850749 hasRelatedWork W3029745265 @default.
- W2320850749 hasRelatedWork W3031637084 @default.
- W2320850749 hasRelatedWork W3031880230 @default.
- W2320850749 hasRelatedWork W3148624402 @default.
- W2320850749 hasRelatedWork W3150602262 @default.
- W2320850749 hasRelatedWork W3168354197 @default.
- W2320850749 isParatext "false" @default.
- W2320850749 isRetracted "false" @default.
- W2320850749 magId "2320850749" @default.
- W2320850749 workType "article" @default.