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• W2320938314 abstract "Event Abstract Back to Event Impact of Anodal and Cathodal transcranial Direct Current Stimulation over the Left Dorsolateral Prefontral Cortex during Attention Bias Modification: an Eye-tracking Study Alexandre Heeren1*, Chris Baeken2, Marie-Anne Vanderhasselt3, Pierre Philippot1 and Rudi De Raedt3 1 Université catholique de Louvain/ Fonds Nationnal de la Recherche Scientifique, Laboratory for experimental Psychopathology, Belgium 2 Ghent University, Department of Psychiatry and Medical Psychology,, Belgium 3 Ghent University, Department of Experimental Clinical and Health Psychology, Belgium People with anxiety disorders show an attentional bias for threat (AB), and Attention Bias Modification (ABM) procedures have been found to reduce this bias. At a fundamental level, however, uncertainty still abounds regarding the nature of the processes that mediate this effect. One explanation suggests that ABM requires the modification of attention control, driven by the recruitment of the dorsolateral prefrontal cortex (DLPFC). In the present double-blind study, we examined whether modifying left DLPFC activation influences the effect of ABM on AB. We used transcranial current direct stimulation (tDCS) to directly modulate cortical excitability of the left DLPFC during ABM. Anodal tDCS increases excitability, whereas cathodal tDCS decreases it. We randomly assigned highly trait-anxious individuals to one of three conditions: 1) ABM combined with cathodal tDCS, 2) ABM combined with anodal tDCS, or 3) ABM combined with sham tDCS. We assessed the effects of these manipulations on both reaction times and eye-movements on a task indexing AB. Results indicate that combining ABM and anodal tDCS over the left DLPFC reduces the total duration that participants’ gaze remains fixated on threat, as assessed using eye-tracking measurement. As the difficulty to disengage attention from threat is known to play an important role in the maintenance of anxiety, this suggest that anodal tDCS over the left DLPFC may be considered as a promising tool to reduce the inability to effectively disengage attention from threat among patients suffering anxiety disorders. Acknowledgements This research was supported by a Grant (FC 78142) from the Belgian National Fund for Scientific Research (awarded to Alexandre Heeren), a Grant (FWO08/PDO/168) from the Research Foundation Flanders (awarded to Marie-Anne Vanderhasselt), a Grant (BOF10/GOA/014) for a Concerted Research Action of Ghent University (awarded to Rudi De Raedt). These funding bodies did not exert any editorial direction or censorship on any part of this article. Keywords: Attentional bias modification, attentional bias, Eye-tracking, DLPFC, tDCS, Neuromodulation, trait-anxiety Conference: Belgian Brain Council 2014 MODULATING THE BRAIN: FACTS, FICTION, FUTURE, Ghent, Belgium, 4 Oct - 4 Oct, 2014. Presentation Type: Poster Presentation Topic: Clinical Neuroscience Citation: Heeren A, Baeken C, Vanderhasselt M, Philippot P and De Raedt R (2014). Impact of Anodal and Cathodal transcranial Direct Current Stimulation over the Left Dorsolateral Prefontral Cortex during Attention Bias Modification: an Eye-tracking Study. Conference Abstract: Belgian Brain Council 2014 MODULATING THE BRAIN: FACTS, FICTION, FUTURE. doi: 10.3389/conf.fnhum.2014.214.00085 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 03 Sep 2014; Published Online: 03 Sep 2014. * Correspondence: Dr. Alexandre Heeren, Université catholique de Louvain/ Fonds Nationnal de la Recherche Scientifique, Laboratory for experimental Psychopathology, Louvain-la-Neuve, Brabant Wallon, 1348, Belgium, alexandre.heeren@uclouvain.be Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Alexandre Heeren Chris Baeken Marie-Anne Vanderhasselt Pierre Philippot Rudi De Raedt Google Alexandre Heeren Chris Baeken Marie-Anne Vanderhasselt Pierre Philippot Rudi De Raedt Google Scholar Alexandre Heeren Chris Baeken Marie-Anne Vanderhasselt Pierre Philippot Rudi De Raedt PubMed Alexandre Heeren Chris Baeken Marie-Anne Vanderhasselt Pierre Philippot Rudi De Raedt Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page." @default.
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• W2320938314 title "Impact of Anodal and Cathodal transcranial Direct Current Stimulation over the Left Dorsolateral Prefontral Cortex during Attention Bias Modification: an Eye-tracking Study" @default.
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