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• W2320939404 abstract "Cerebral aneurysms can be treated by coil embolization within the aneurysm sac to alter the local hemodynamics and lower the wall shear stress (WSS) by making the aneurysmal flow inactive. This study investigates the hemodynamics of a lateral wall cerebral aneurysm with coils incorporating fluid-structure interaction (FSI) where the effect of apparent viscosity on thrombus formation is analysed considering the non-Newtonian behaviour of the blood. Three-dimensional transient incompressible laminar flow fields were predicted inside the aneurysm with coils at the proximal and distal neck ends with straight and curved parent vessels. The predictions showed the WSS and the effective stress were highest at the neck region, but the maximum wall displacement occurred at the dome. The coils at the distal neck performed better compared to the coils at the proximal neck in terms of reduced flow rate and higher apparent viscosity. The cerebral aneurysm with coils and curved parent vessel was subjected to higher inflow, displacement and WSS but lower apparent viscosity compared to the one with a straight parent vessel, and therefore has a greater risk of aneurysm wall damage. Hypertension increased the effective stress and displacement on the aneurysm. In patients with hypertension, more emphasis should be placed on ensuring that coils are densely packed at the distal end, especially for curved parent vessels." @default.
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• W2320939404 date "2011-01-01" @default.
• W2320939404 modified "2023-10-08" @default.
• W2320939404 title "Numerical Investigation of Hemodynamics of Lateral Cerebral Aneurysm Following Coil Embolization" @default.
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• W2320939404 doi "https://doi.org/10.1080/19942060.2011.11015375" @default.
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