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- W2321195624 abstract "The effect of a short treatment (7 days) with citalopram on the reactivity to inhalations of 35% CO 2 and 65% oxygen and on clinical symptomatology was investigated in 15 patients with panic disorder who had a positive response to 35% CO 2 inhalation. An open study design was applied. On day 0, before starting drug treatment, and after 1 week of treatment, each patient underwent the 35% CO 2 challenge, and clinical symptomatology was evaluated with psychometric scales. The results showed a significant reduction of CO 2 reactivity and of scores on the anticipatory anxiety subscale of Panic Associated Symptoms Scale. These results confirm that the serotonergic system plays an important role in the modulation of CO 2 hyperreactivity and suggest an early anxiolytic effect of citalopram in patients who have panic disorder and are hyperreactive to CO 2 ." @default.
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- W2321195624 date "2001-06-01" @default.
- W2321195624 modified "2023-09-26" @default.
- W2321195624 title "The 35% CO 2 Hyperreactivity and Clinical Symptomatology in Patients With Panic Disorder After 1 Week of Treatment With Citalopram: An Open Study" @default.
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- W2321195624 doi "https://doi.org/10.1097/00004714-200106000-00003" @default.
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