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- W2321229043 abstract "Every therapeutic agent of value has its potential dangers and hyperpyrexia is no exception to this general rule. Two of the most constant pathologic findings following induced fever in experimental animals and in human subjects are hemorrhage and acute parenchymatous degeneration of the liver. Hartman1 has pointed out the similarity of these pathologic changes to those encountered following prolonged mild asphyxia, and has demonstrated that anoxia is a common accompaniment of artificially induced fever.The mechanism underlying the hemorrhage following artificially induced fever has never been entirely satisfactorily explained. In the present study selected cellular and humoral factors important in the complex phenomenon of blood coagulation have been determined under experimental conditions in rabbits and during fever therapy in human patients. Total platelet counts have been correlated with qualitative and quantitative studies of the megakaryocytes in serial marrow punctures; quantitative prothrombin an..." @default.
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- W2321229043 date "1939-05-01" @default.
- W2321229043 modified "2023-09-27" @default.
- W2321229043 title "Pathogenesis of Hemorrhage in Artificially Induced Fever" @default.
- W2321229043 doi "https://doi.org/10.3181/00379727-41-10589p" @default.
- W2321229043 hasPublicationYear "1939" @default.
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