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- W2321242469 abstract "Two new indole spermidine alkaloids, didemnidines A (1) and B (2), have been isolated from the New Zealand ascidian Didemnum sp. The structures of the metabolites, determined by analysis of 2D NMR spectra and confirmed via synthesis, embody an indole-3-glyoxylamide moiety linked to the N(1) position of spermidine, the latter motif being particularly rare among marine natural products. Didemnidine B and a synthetic precursor exhibited mild in vitro growth inhibition of Plasmodium falciparum with IC(50)'s of 15 and 8.4 μM, respectively." @default.
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- W2321242469 date "2011-02-24" @default.
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- W2321242469 title "Didemnidines A and B, Indole Spermidine Alkaloids from the New Zealand Ascidian <i>Didemnum </i>sp." @default.
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- W2321242469 doi "https://doi.org/10.1021/np1008619" @default.
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