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• W2321358712 abstract "Platelet-rich plasma (PRP) is a matrix of fibrin and platelets that releases cytokines that are important in wound healing. PRP is produced from the patient's blood and therefore has less risk of allergic reaction and infection. We have obtained PRP with an enhanced white blood cell component (W-PRP) by optimizing the centrifugal separation of PRP from plasma. Here we show that injection of W-PRP into the auricle of nude mice gave greater tissue augmentation compared to PRP. Further augmentation occurred when bFGF was added to W-PRP, and there was a significant increase in the number of α-smooth muscle actin-positive cells in mice treated with W-PRP+bFGF. Our results suggest that W-PRP may have value in cosmetic surgery aimed at rejuvenation of wrinkled and sagging skin. W-PRP injection constitutes a new concept in cell transplantation, in which cells required for tissue regeneration are induced by cytokines released from the transplanted cells." @default.
• W2321358712 created "2016-06-24" @default.
• W2321358712 creator A5047340235 @default.
• W2321358712 creator A5076623237 @default.
• W2321358712 date "2012-03-01" @default.
• W2321358712 modified "2023-09-26" @default.
• W2321358712 title "Tissue Augmentation by White Blood Cell-Containing Platelet-Rich Plasma" @default.
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• W2321358712 doi "https://doi.org/10.3727/096368911x605538" @default.
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