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- W2321480188 abstract "慢性肝炎,肝硬変における細胞性癌遺伝子c-myc, c-Ha-rasの発現を間接酵素抗体法を用いて検討した.c-myc, c-Ha-rasは非B型慢性肝疾患(c-myc 11.1%, c-Ha-ras 5.6%)に比しB型慢性肝疾患(c-myc 37.5%, c-Ha-ras 25.0%)で高率に発現していた.また,B型慢性肝疾患においてはc-myc発現率はX蛋白発現例で有意に高く,c-Ha-ras発現率はX蛋白発現例およびC抗原発現例で高い傾向にあった.c-mycおよびc-Ha-ras発現例ではHBe抗原陽性率,DNAポリメラーゼ値,α-フェトプロテイン値が高い傾向にあり,B型肝炎ウイルスの旺盛な増殖による肝細胞の壊死・再生がc-mycおよびc-Ha-rasの発現に関与することが示唆された." @default.
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- W2321480188 date "1990-01-01" @default.
- W2321480188 modified "2023-09-25" @default.
- W2321480188 title "The expression of c-myc and c-Ha-ras products in chronic liver disease." @default.
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- W2321480188 doi "https://doi.org/10.2957/kanzo.31.118" @default.
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