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- W232152922 abstract "Recently, we established an in vivo method to directly and continuously monitor and evaluate O2 using an electrochemical O2 sensor. The generated O2 is measured as a current and evaluated as a difference in the current from the baseline to the actual reacted O2 current (ΔI) and a quantified partial value of electricity (Q), which is calculated by integration of differences between baseline and actual reacted current. To clarify the dynamics of O2 in vivo and their O2-related pathophysiology, the accuracy and efficacy of this method were confirmed in phosphate-buffered saline and human blood and we applied this sensor to rat models of endotoxemia, forebrain ischemia-reperfusion (FBI/R), and heatstroke. This is a novel method for measuring O2 in vivo, and could be used to monitor and treat the pathophysiology caused by excessive O2 generation in animals and humans." @default.
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- W232152922 date "2012-01-01" @default.
- W232152922 modified "2023-09-26" @default.
- W232152922 title "In vivo real-time monitoring and evaluation for superoxide anion radical generation with an electrochemical sensor" @default.
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