Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321555219> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2321555219 endingPage "1687" @default.
- W2321555219 startingPage "1677" @default.
- W2321555219 abstract "Aims: The crude methanol extract of whole plant of Blumea lacera (Burn.f.) DC. has been investigated for anti-diarrheal, antimicrobial, anxiolytic, anti-atherothrombosis, membrane stabilizing and alpha-amylase inhibitory activities.Place and Duration of Study: The study was carried out in 2013 in the Department of Pharmacy, Southern University Bangladesh, Chittagong, Bangladesh.Methodology: Test for anti-diarrheal activity was carried out by castor oil-induced diarrhea in mice. The preliminary antimicrobial activity was determined by the agar disc diffusion method. The anxiolytic activity was examined in mice by using the hole board test and open field test (OFT). The anti-atherothrombosis activity was evaluated using standard streptokinase. The membrane stabilizing activity was assessed by using hypotonic solution induced hemolysis of human erythrocyte. The plant extract was also assessed for anti-diabetic ability using In vitro α-amylase inhibitory potential. The α-amylase inhibitory activity of B. lacera was measured using the starch-iodine method.Results: The crude extract of B. lacera showed anti-diarrheal activity in dose-dependent manner. In antimicrobial assay, this extract showed better activity against the tested fungi compared to the bacteria used in the screening. Significant anxiolytic activity was found for this plant extract. In the In vitro anti-atherothrombosis test, the extract exhibited 46.17% clot lysis as compared to the standard, streptokinase (81.53%). In membrane stabilizing activity test, the plant extract at 1.0mg/ml inhibited the heat-induced hemolysis of RBCs by 52.27% whereas the standard acetyl salicylic acid (ASA) demonstrated 81.72% inhibition of hemolysis. Our results revealed that the extract had dose dependent prevention of digestion of carbohydrates by inhibiting α-amylase. The ability of B. lacera to inhibit thermal-and hypotonic-enzyme activity was found to be statistically significant (p=0.05).Conclusion: These results demonstrated that B. lacera may be used in pharmaceutical applications because of its effective pharmacological properties." @default.
- W2321555219 created "2016-06-24" @default.
- W2321555219 creator A5018007363 @default.
- W2321555219 creator A5028195330 @default.
- W2321555219 creator A5059423763 @default.
- W2321555219 creator A5085255814 @default.
- W2321555219 creator A5085365887 @default.
- W2321555219 creator A5089589298 @default.
- W2321555219 creator A5091580850 @default.
- W2321555219 date "2014-01-10" @default.
- W2321555219 modified "2023-10-16" @default.
- W2321555219 title "Pharmacological Activities of Blumea lacera (Burm. f) DC: A Medicinal Plant of Bangladesh" @default.
- W2321555219 cites W1494180074 @default.
- W2321555219 cites W1535288212 @default.
- W2321555219 cites W1548329918 @default.
- W2321555219 cites W1842584044 @default.
- W2321555219 cites W1963506876 @default.
- W2321555219 cites W1997731630 @default.
- W2321555219 cites W2014094015 @default.
- W2321555219 cites W2020411326 @default.
- W2321555219 cites W2027877938 @default.
- W2321555219 cites W2054398949 @default.
- W2321555219 cites W2059805912 @default.
- W2321555219 cites W2062821426 @default.
- W2321555219 cites W2067667460 @default.
- W2321555219 cites W2077946722 @default.
- W2321555219 cites W2087454739 @default.
- W2321555219 cites W2128107114 @default.
- W2321555219 cites W2129289295 @default.
- W2321555219 cites W2132963724 @default.
- W2321555219 cites W2149691555 @default.
- W2321555219 cites W2151096481 @default.
- W2321555219 cites W2151381931 @default.
- W2321555219 cites W2168339235 @default.
- W2321555219 cites W2169274012 @default.
- W2321555219 cites W2183851261 @default.
- W2321555219 cites W2566717541 @default.
- W2321555219 doi "https://doi.org/10.9734/bjpr/2014/10001" @default.
- W2321555219 hasPublicationYear "2014" @default.
- W2321555219 type Work @default.
- W2321555219 sameAs 2321555219 @default.
- W2321555219 citedByCount "9" @default.
- W2321555219 countsByYear W23215552192016 @default.
- W2321555219 countsByYear W23215552192017 @default.
- W2321555219 countsByYear W23215552192020 @default.
- W2321555219 countsByYear W23215552192023 @default.
- W2321555219 crossrefType "journal-article" @default.
- W2321555219 hasAuthorship W2321555219A5018007363 @default.
- W2321555219 hasAuthorship W2321555219A5028195330 @default.
- W2321555219 hasAuthorship W2321555219A5059423763 @default.
- W2321555219 hasAuthorship W2321555219A5085255814 @default.
- W2321555219 hasAuthorship W2321555219A5085365887 @default.
- W2321555219 hasAuthorship W2321555219A5089589298 @default.
- W2321555219 hasAuthorship W2321555219A5091580850 @default.
- W2321555219 hasBestOaLocation W23215552191 @default.
- W2321555219 hasConcept C178790620 @default.
- W2321555219 hasConcept C185592680 @default.
- W2321555219 hasConcept C203014093 @default.
- W2321555219 hasConcept C2779902561 @default.
- W2321555219 hasConcept C4937899 @default.
- W2321555219 hasConcept C556039675 @default.
- W2321555219 hasConcept C71924100 @default.
- W2321555219 hasConcept C98274493 @default.
- W2321555219 hasConceptScore W2321555219C178790620 @default.
- W2321555219 hasConceptScore W2321555219C185592680 @default.
- W2321555219 hasConceptScore W2321555219C203014093 @default.
- W2321555219 hasConceptScore W2321555219C2779902561 @default.
- W2321555219 hasConceptScore W2321555219C4937899 @default.
- W2321555219 hasConceptScore W2321555219C556039675 @default.
- W2321555219 hasConceptScore W2321555219C71924100 @default.
- W2321555219 hasConceptScore W2321555219C98274493 @default.
- W2321555219 hasIssue "13" @default.
- W2321555219 hasLocation W23215552191 @default.
- W2321555219 hasOpenAccess W2321555219 @default.
- W2321555219 hasPrimaryLocation W23215552191 @default.
- W2321555219 hasRelatedWork W114143151 @default.
- W2321555219 hasRelatedWork W2012011796 @default.
- W2321555219 hasRelatedWork W2056412123 @default.
- W2321555219 hasRelatedWork W2057124342 @default.
- W2321555219 hasRelatedWork W2095212420 @default.
- W2321555219 hasRelatedWork W2095399821 @default.
- W2321555219 hasRelatedWork W2396822601 @default.
- W2321555219 hasRelatedWork W2949587191 @default.
- W2321555219 hasRelatedWork W3145077582 @default.
- W2321555219 hasRelatedWork W4312052875 @default.
- W2321555219 hasVolume "4" @default.
- W2321555219 isParatext "false" @default.
- W2321555219 isRetracted "false" @default.
- W2321555219 magId "2321555219" @default.
- W2321555219 workType "article" @default.