FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321584584> ?p ?o ?g. }

• W2321584584 endingPage "2270" @default.
• W2321584584 startingPage "2264" @default.
• W2321584584 abstract "Background: Target anticoagulation levels for warfarin in Japanese patients with non-valvular atrial fibrillation (NVAF) are unclear. Methods and Results: Of 7,527 patients with NVAF, 1,002 did not receive warfarin (non-warfarin group), and the remaining patients receiving warfarin were divided into 5 groups based on their baseline international normalized ratio (INR) of prothrombin time (≤1.59, 1.6–1.99, 2.0–2.59, 2.6–2.99, and ≥3.0). Patients were followed-up prospectively for 2 years. Primary endpoints were thromboembolic events (cerebral infarction, transient ischemic attack, and systemic embolism), and major hemorrhage requiring hospital admission. During the follow-up period, thromboembolic events occurred in 3.0% of non-warfarin group, but at lower frequencies in the warfarin groups (2.0, 1.3, 1.5, 0.6, and 1.8%/2 years for INR values of ≤1.59, 1.6–1.99, 2.0–2.59, 2.6–2.99, and ≥3.0, respectively; P=0.0059). Major hemorrhage occurred more frequently in warfarin groups (1.5, 1.8, 2.4, 3.3, and 4.1% for INR values ≤1.59, 1.6–1.99, 2.0–2.59, 2.6–2.99, and ≥3.0, respectively; P=0.0041) than in non-warfarin group (0.8%/2 years). These trends were maintained when the analyses were confined to patients aged ≥70 years. Conclusions: An INR of 1.6–2.6 is safe and effective at preventing thromboembolic events in patients with NVAF, particularly patients aged ≥70 years. An INR of 2.6–2.99 is also effective, but associated with a slightly increased risk in major hemorrhage. (UMIN Clinical Trials Registry UMIN000001569) (Circ J 2013; 77: 2264–2270)" @default.
• W2321584584 created "2016-06-24" @default.
• W2321584584 creator A5002489205 @default.
• W2321584584 creator A5004300203 @default.
• W2321584584 creator A5009147715 @default.
• W2321584584 creator A5011453870 @default.
• W2321584584 creator A5018539336 @default.
• W2321584584 creator A5023742411 @default.
• W2321584584 creator A5030012941 @default.
• W2321584584 creator A5034361977 @default.
• W2321584584 creator A5036381262 @default.
• W2321584584 creator A5036800804 @default.
• W2321584584 creator A5042772429 @default.
• W2321584584 creator A5046310953 @default.
• W2321584584 creator A5049171023 @default.
• W2321584584 creator A5054911802 @default.
• W2321584584 creator A5055227838 @default.
• W2321584584 creator A5055983723 @default.
• W2321584584 creator A5062948954 @default.
• W2321584584 creator A5063130877 @default.
• W2321584584 creator A5063289204 @default.
• W2321584584 creator A5066866386 @default.
• W2321584584 creator A5070211202 @default.
• W2321584584 creator A5072169946 @default.
• W2321584584 creator A5079500797 @default.
• W2321584584 creator A5087992950 @default.
• W2321584584 date "2013-01-01" @default.
• W2321584584 modified "2023-10-17" @default.
• W2321584584 title "Target International Normalized Ratio Values for Preventing Thromboembolic and Hemorrhagic Events in Japanese Patients With Non-Valvular Atrial Fibrillation" @default.
• W2321584584 cites W1506966900 @default.
• W2321584584 cites W1586488555 @default.
• W2321584584 cites W1999496937 @default.
• W2321584584 cites W2015696505 @default.
• W2321584584 cites W2023143117 @default.
• W2321584584 cites W2067927562 @default.
• W2321584584 cites W2070567676 @default.
• W2321584584 cites W2081205482 @default.
• W2321584584 cites W2082168979 @default.
• W2321584584 cites W2103053426 @default.
• W2321584584 cites W2119905314 @default.
• W2321584584 cites W2120064023 @default.
• W2321584584 cites W2152115221 @default.
• W2321584584 cites W2159730165 @default.
• W2321584584 cites W2163012396 @default.
• W2321584584 cites W2166866093 @default.
• W2321584584 cites W2170421103 @default.
• W2321584584 cites W2320128544 @default.
• W2321584584 cites W3151733905 @default.
• W2321584584 cites W646388154 @default.
• W2321584584 doi "https://doi.org/10.1253/circj.cj-13-0290" @default.
• W2321584584 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23708863" @default.
• W2321584584 hasPublicationYear "2013" @default.
• W2321584584 type Work @default.
• W2321584584 sameAs 2321584584 @default.
• W2321584584 citedByCount "115" @default.
• W2321584584 countsByYear W23215845842013 @default.
• W2321584584 countsByYear W23215845842014 @default.
• W2321584584 countsByYear W23215845842015 @default.
• W2321584584 countsByYear W23215845842016 @default.
• W2321584584 countsByYear W23215845842017 @default.
• W2321584584 countsByYear W23215845842018 @default.
• W2321584584 countsByYear W23215845842019 @default.
• W2321584584 countsByYear W23215845842020 @default.
• W2321584584 countsByYear W23215845842021 @default.
• W2321584584 countsByYear W23215845842022 @default.
• W2321584584 countsByYear W23215845842023 @default.
• W2321584584 crossrefType "journal-article" @default.
• W2321584584 hasAuthorship W2321584584A5002489205 @default.
• W2321584584 hasAuthorship W2321584584A5004300203 @default.
• W2321584584 hasAuthorship W2321584584A5009147715 @default.
• W2321584584 hasAuthorship W2321584584A5011453870 @default.
• W2321584584 hasAuthorship W2321584584A5018539336 @default.
• W2321584584 hasAuthorship W2321584584A5023742411 @default.
• W2321584584 hasAuthorship W2321584584A5030012941 @default.
• W2321584584 hasAuthorship W2321584584A5034361977 @default.
• W2321584584 hasAuthorship W2321584584A5036381262 @default.
• W2321584584 hasAuthorship W2321584584A5036800804 @default.
• W2321584584 hasAuthorship W2321584584A5042772429 @default.
• W2321584584 hasAuthorship W2321584584A5046310953 @default.
• W2321584584 hasAuthorship W2321584584A5049171023 @default.
• W2321584584 hasAuthorship W2321584584A5054911802 @default.
• W2321584584 hasAuthorship W2321584584A5055227838 @default.
• W2321584584 hasAuthorship W2321584584A5055983723 @default.
• W2321584584 hasAuthorship W2321584584A5062948954 @default.
• W2321584584 hasAuthorship W2321584584A5063130877 @default.
• W2321584584 hasAuthorship W2321584584A5063289204 @default.
• W2321584584 hasAuthorship W2321584584A5066866386 @default.
• W2321584584 hasAuthorship W2321584584A5070211202 @default.
• W2321584584 hasAuthorship W2321584584A5072169946 @default.
• W2321584584 hasAuthorship W2321584584A5079500797 @default.
• W2321584584 hasAuthorship W2321584584A5087992950 @default.
• W2321584584 hasBestOaLocation W23215845841 @default.
• W2321584584 hasConcept C126322002 @default.
• W2321584584 hasConcept C127413603 @default.
• W2321584584 hasConcept C164705383 @default.
• W2321584584 hasConcept C2776301958 @default.
• W2321584584 hasConcept C2777185221 @default.
• W2321584584 hasConcept C2779161974 @default.

• next