FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321709204> ?p ?o ?g. }

• W2321709204 endingPage "561" @default.
• W2321709204 startingPage "555" @default.
• W2321709204 abstract "Antigen-driven selection has been implicated in the pathogenesis of monoclonal gammopathies. Patients with Gaucher's disease have an increased risk of monoclonal gammopathies. Here we show that the clonal immunoglobulin in patients with Gaucher's disease and in mouse models of Gaucher's disease-associated gammopathy is reactive against lyso-glucosylceramide (LGL1), which is markedly elevated in these patients and mice. Clonal immunoglobulin in 33% of sporadic human monoclonal gammopathies is also specific for the lysolipids LGL1 and lysophosphatidylcholine (LPC). Substrate reduction ameliorates Gaucher's disease-associated gammopathy in mice. Thus, long-term immune activation by lysolipids may underlie both Gaucher's disease-associated gammopathies and some sporadic monoclonal gammopathies." @default.
• W2321709204 created "2016-06-24" @default.
• W2321709204 creator A5027835055 @default.
• W2321709204 creator A5032177345 @default.
• W2321709204 creator A5039748385 @default.
• W2321709204 creator A5055529584 @default.
• W2321709204 creator A5059291260 @default.
• W2321709204 creator A5088696429 @default.
• W2321709204 date "2016-02-11" @default.
• W2321709204 modified "2023-10-17" @default.
• W2321709204 title "Clonal Immunoglobulin against Lysolipids in the Origin of Myeloma" @default.
• W2321709204 cites W1483933457 @default.
• W2321709204 cites W1975902496 @default.
• W2321709204 cites W1978796728 @default.
• W2321709204 cites W1989712414 @default.
• W2321709204 cites W1992638794 @default.
• W2321709204 cites W2006013727 @default.
• W2321709204 cites W2008798354 @default.
• W2321709204 cites W2010935915 @default.
• W2321709204 cites W2011184799 @default.
• W2321709204 cites W2021558283 @default.
• W2321709204 cites W2026402856 @default.
• W2321709204 cites W2028245787 @default.
• W2321709204 cites W2038435728 @default.
• W2321709204 cites W2042840742 @default.
• W2321709204 cites W2044378421 @default.
• W2321709204 cites W2047381753 @default.
• W2321709204 cites W2047653786 @default.
• W2321709204 cites W2087510980 @default.
• W2321709204 cites W2094194262 @default.
• W2321709204 cites W2094632651 @default.
• W2321709204 cites W2262927932 @default.
• W2321709204 cites W226917763 @default.
• W2321709204 cites W2314253416 @default.
• W2321709204 cites W2397666787 @default.
• W2321709204 cites W4252175385 @default.
• W2321709204 doi "https://doi.org/10.1056/nejmoa1508808" @default.
• W2321709204 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4804194" @default.
• W2321709204 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26863356" @default.
• W2321709204 hasPublicationYear "2016" @default.
• W2321709204 type Work @default.
• W2321709204 sameAs 2321709204 @default.
• W2321709204 citedByCount "157" @default.
• W2321709204 countsByYear W23217092042016 @default.
• W2321709204 countsByYear W23217092042017 @default.
• W2321709204 countsByYear W23217092042018 @default.
• W2321709204 countsByYear W23217092042019 @default.
• W2321709204 countsByYear W23217092042020 @default.
• W2321709204 countsByYear W23217092042021 @default.
• W2321709204 countsByYear W23217092042022 @default.
• W2321709204 countsByYear W23217092042023 @default.
• W2321709204 crossrefType "journal-article" @default.
• W2321709204 hasAuthorship W2321709204A5027835055 @default.
• W2321709204 hasAuthorship W2321709204A5032177345 @default.
• W2321709204 hasAuthorship W2321709204A5039748385 @default.
• W2321709204 hasAuthorship W2321709204A5055529584 @default.
• W2321709204 hasAuthorship W2321709204A5059291260 @default.
• W2321709204 hasAuthorship W2321709204A5088696429 @default.
• W2321709204 hasBestOaLocation W23217092041 @default.
• W2321709204 hasConcept C142724271 @default.
• W2321709204 hasConcept C159654299 @default.
• W2321709204 hasConcept C163864487 @default.
• W2321709204 hasConcept C203014093 @default.
• W2321709204 hasConcept C2776364478 @default.
• W2321709204 hasConcept C2776553844 @default.
• W2321709204 hasConcept C2777250017 @default.
• W2321709204 hasConcept C2779134260 @default.
• W2321709204 hasConcept C2780898057 @default.
• W2321709204 hasConcept C2909204789 @default.
• W2321709204 hasConcept C2909682104 @default.
• W2321709204 hasConcept C542903549 @default.
• W2321709204 hasConcept C71924100 @default.
• W2321709204 hasConceptScore W2321709204C142724271 @default.
• W2321709204 hasConceptScore W2321709204C159654299 @default.
• W2321709204 hasConceptScore W2321709204C163864487 @default.
• W2321709204 hasConceptScore W2321709204C203014093 @default.
• W2321709204 hasConceptScore W2321709204C2776364478 @default.
• W2321709204 hasConceptScore W2321709204C2776553844 @default.
• W2321709204 hasConceptScore W2321709204C2777250017 @default.
• W2321709204 hasConceptScore W2321709204C2779134260 @default.
• W2321709204 hasConceptScore W2321709204C2780898057 @default.
• W2321709204 hasConceptScore W2321709204C2909204789 @default.
• W2321709204 hasConceptScore W2321709204C2909682104 @default.
• W2321709204 hasConceptScore W2321709204C542903549 @default.
• W2321709204 hasConceptScore W2321709204C71924100 @default.
• W2321709204 hasIssue "6" @default.
• W2321709204 hasLocation W23217092041 @default.
• W2321709204 hasLocation W23217092042 @default.
• W2321709204 hasLocation W23217092043 @default.
• W2321709204 hasLocation W23217092044 @default.
• W2321709204 hasOpenAccess W2321709204 @default.
• W2321709204 hasPrimaryLocation W23217092041 @default.
• W2321709204 hasRelatedWork W1992037208 @default.
• W2321709204 hasRelatedWork W2040781198 @default.
• W2321709204 hasRelatedWork W2091774785 @default.
• W2321709204 hasRelatedWork W2139588457 @default.
• W2321709204 hasRelatedWork W22106273 @default.
• W2321709204 hasRelatedWork W2271653665 @default.

• next