FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321801073> ?p ?o ?g. }

• W2321801073 endingPage "216" @default.
• W2321801073 startingPage "210" @default.
• W2321801073 abstract "A significant proportion of patients receiving dual antiplatelet therapy following percutaneous coronary intervention experience recurrent ischaemic events despite standard doses of treatment. Although clinical studies show significant heterogeneity in antiplatelet therapy responses, routine testing is not undertaken due to (i) lack of a standardized test, and (ii) poor clarity with regards to definition of abnormal responses. Short Thrombelastography (s-TEG) is a validated test that allows rapid measurement of clotting responses to antiplatelet therapy.This study sought to determine the reproducibility of s-TEG and to compare s-TEG with VerifyNow in assessment of responses to antiplatelet therapy.(i) intra-individual variability was assessed using s-TEG Area Under the Curve (AUC15) and maximum amplitude (MA) in one volunteer at 20 time-points on no medication and at 10 time-points pre and post 300 mg aspirin treatment (ii) inter-individual variability was determined from a retrospective analysis of data on MA and AUC15 obtained from 56 volunteers on no medication, 25 volunteers pre and post 300 mg aspirin treatment and 28 patients pre and post 600 mg clopidogrel treatment (iii) a comparison between AUC15 arachidonic-acid (AA) channel and VerifyNow aspirin response units (VN ARU) and between AUC15 adenosine diphosphate (ADP) channel and VerifyNow P2Y12 reactivity units (VN PRU) was obtained from retrospective analysis of data at 370 and 296 time-points respectively.There was minimal intra-and inter-individual variability in MA and AUC15 in the AA, ADP and thrombin channels. There was a good correlation between AA AUC15 and VN ARU (r = 0.701, p < 0.001) and between ADP AUC15 and VN PRU (r = 0.609, p < 0.001).s-TEG is a reproducible and reliable near-patient test that correlates well with VerifyNow. Large scale studies are needed to determine its potential role in individually tailored antiplatelet therapy." @default.
• W2321801073 created "2016-06-24" @default.
• W2321801073 creator A5022361618 @default.
• W2321801073 creator A5030616813 @default.
• W2321801073 creator A5044086334 @default.
• W2321801073 date "2011-01-13" @default.
• W2321801073 modified "2023-09-25" @default.
• W2321801073 title "“Short” thrombelastography as a test of platelet reactivity in response to antiplatelet therapy: Validation and reproducibility" @default.
• W2321801073 cites W141287021 @default.
• W2321801073 cites W1524907070 @default.
• W2321801073 cites W1726466368 @default.
• W2321801073 cites W1969822008 @default.
• W2321801073 cites W1974655135 @default.
• W2321801073 cites W1985018076 @default.
• W2321801073 cites W2001287599 @default.
• W2321801073 cites W2014471201 @default.
• W2321801073 cites W2022537971 @default.
• W2321801073 cites W2026903778 @default.
• W2321801073 cites W2034031223 @default.
• W2321801073 cites W2039397424 @default.
• W2321801073 cites W2056384040 @default.
• W2321801073 cites W2056425903 @default.
• W2321801073 cites W2058874291 @default.
• W2321801073 cites W2060063218 @default.
• W2321801073 cites W2067737545 @default.
• W2321801073 cites W2072386538 @default.
• W2321801073 cites W2082992076 @default.
• W2321801073 cites W2083134865 @default.
• W2321801073 cites W2086599873 @default.
• W2321801073 cites W2090438280 @default.
• W2321801073 cites W2102309294 @default.
• W2321801073 cites W2110278285 @default.
• W2321801073 cites W2110897264 @default.
• W2321801073 cites W2136682527 @default.
• W2321801073 cites W2137908623 @default.
• W2321801073 cites W2145126811 @default.
• W2321801073 cites W2147294426 @default.
• W2321801073 cites W2160351087 @default.
• W2321801073 cites W2161043271 @default.
• W2321801073 cites W2165620610 @default.
• W2321801073 cites W2168183862 @default.
• W2321801073 cites W2230985493 @default.
• W2321801073 cites W4232642121 @default.
• W2321801073 cites W4250866529 @default.
• W2321801073 doi "https://doi.org/10.3109/09537104.2010.543201" @default.
• W2321801073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21231856" @default.
• W2321801073 hasPublicationYear "2011" @default.
• W2321801073 type Work @default.
• W2321801073 sameAs 2321801073 @default.
• W2321801073 citedByCount "27" @default.
• W2321801073 countsByYear W23218010732012 @default.
• W2321801073 countsByYear W23218010732013 @default.
• W2321801073 countsByYear W23218010732014 @default.
• W2321801073 countsByYear W23218010732015 @default.
• W2321801073 countsByYear W23218010732016 @default.
• W2321801073 countsByYear W23218010732017 @default.
• W2321801073 countsByYear W23218010732018 @default.
• W2321801073 countsByYear W23218010732020 @default.
• W2321801073 countsByYear W23218010732022 @default.
• W2321801073 crossrefType "journal-article" @default.
• W2321801073 hasAuthorship W2321801073A5022361618 @default.
• W2321801073 hasAuthorship W2321801073A5030616813 @default.
• W2321801073 hasAuthorship W2321801073A5044086334 @default.
• W2321801073 hasConcept C105795698 @default.
• W2321801073 hasConcept C126322002 @default.
• W2321801073 hasConcept C164705383 @default.
• W2321801073 hasConcept C167135981 @default.
• W2321801073 hasConcept C2777628954 @default.
• W2321801073 hasConcept C2777664302 @default.
• W2321801073 hasConcept C2777849778 @default.
• W2321801073 hasConcept C2780400711 @default.
• W2321801073 hasConcept C2910686401 @default.
• W2321801073 hasConcept C33923547 @default.
• W2321801073 hasConcept C42219234 @default.
• W2321801073 hasConcept C49059817 @default.
• W2321801073 hasConcept C500558357 @default.
• W2321801073 hasConcept C71924100 @default.
• W2321801073 hasConcept C89560881 @default.
• W2321801073 hasConcept C9893847 @default.
• W2321801073 hasConceptScore W2321801073C105795698 @default.
• W2321801073 hasConceptScore W2321801073C126322002 @default.
• W2321801073 hasConceptScore W2321801073C164705383 @default.
• W2321801073 hasConceptScore W2321801073C167135981 @default.
• W2321801073 hasConceptScore W2321801073C2777628954 @default.
• W2321801073 hasConceptScore W2321801073C2777664302 @default.
• W2321801073 hasConceptScore W2321801073C2777849778 @default.
• W2321801073 hasConceptScore W2321801073C2780400711 @default.
• W2321801073 hasConceptScore W2321801073C2910686401 @default.
• W2321801073 hasConceptScore W2321801073C33923547 @default.
• W2321801073 hasConceptScore W2321801073C42219234 @default.
• W2321801073 hasConceptScore W2321801073C49059817 @default.
• W2321801073 hasConceptScore W2321801073C500558357 @default.
• W2321801073 hasConceptScore W2321801073C71924100 @default.
• W2321801073 hasConceptScore W2321801073C89560881 @default.
• W2321801073 hasConceptScore W2321801073C9893847 @default.
• W2321801073 hasIssue "3" @default.
• W2321801073 hasLocation W23218010731 @default.
• W2321801073 hasLocation W23218010732 @default.

• next