Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321801667> ?p ?o ?g. }
- W2321801667 abstract "Immunologists have recently taken note of the fact that a host not only resists infection, but also exhibits a capacity to manage the pathology associated with such infection - a concept referred to as tolerance. Here we explore how the tolerance/resistance (T/R) framework can be implemented within an oncological context and explore a number of implications. In particular, the T/R framework distinguishes between pathology manifesting from extensive tumor burden, versus cancers intrinsically expressing a more pathogenic phenotype. Consequently, the T/R framework provides novel methodology in studying the nature of cancer pathology and for marker identification. Additionally, this framework may aid in redefining the therapeutic end point under suitable circumstances: establishing cancer as a chronic, manageable disease." @default.
- W2321801667 created "2016-06-24" @default.
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- W2321801667 date "2016-06-01" @default.
- W2321801667 modified "2023-09-27" @default.
- W2321801667 title "Cancer tolerance, resistance, pathogenicity and virulence: deconstructing the disease state" @default.
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- W2321801667 doi "https://doi.org/10.2217/fon-2015-0024" @default.
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