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- W2321805450 abstract "Patients with end-stage heart failure are at high risk for vitamin D deficiency because of limited sunlight exposure, reduced intestinal absorption, and hepatorenal disease. But there is a lack of information about the prevalence and severity of vitamin D deficiency in LVAD patients who have an improved hemodynamic situation. Thirteen patients with a left ventricular assist device (LVAD, HVAD, Heart Ware) were evaluated in our outpatient VAD clinics. Mean age was 56±2 yr and ten patients were male (76.9%). Eight patients (61.5%) had non-ischemic cardiomypathy. Indications for VAD implantation were BTT in six (46.2%) and destination therapy in seven (53.8%) patients. Mean time on device were 399 ± 292 days. Vitamin D insufficiency was defined as serum 25-hydroxy-vitamin D level (25OHD) less than 30 ng/L, the threshold commonly used to denote sufficiency. Mean 25OHD level was 22 ± 4 ng/L. 77% had levels below 30 ng/L,. Severe deficiency (25OHD level <15 ng/L) was found in 46%. (Figure 1) 25OHD did not differ by age, gender or indication. Vitamin D deficiency is highly prevalent among LVAD patients. As vitamin D deficiency has many serious skeletal and extra-skeletal sequelae, physicians who treat LVAD patients should maintain a high degree of vigilance for this problem. However, further studies are needed to confirm a benefit of Vitamin D substitution on patient outcomes." @default.
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- W2321805450 date "2014-04-01" @default.
- W2321805450 modified "2023-09-23" @default.
- W2321805450 title "Prevalence of Vitamin D Deficiency Among LVAD Patients" @default.
- W2321805450 doi "https://doi.org/10.1016/j.healun.2014.01.902" @default.
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