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- W2321808643 abstract "Despite a worldwide increase in the presence of methicillin-resistant Staphylococcus pseudintermedius (MRSP) in dogs and its potential to cause serious canine health problem, the understanding of the transmission and long-term carriage of MRSP is limited. The objective of this study was to investigate the transmission of MRSP to contact dogs living in multiple dog households where one or more of the dogs had been diagnosed with a clinically apparent infection with MRSP. MRSP carriage was investigated over several months in 11 dogs living in four separate multiple dog households where an MRSP infection in a dog had been diagnosed. Whole-genome sequencing was used for genotypic characterization. Contact dogs were only MRSP-positive if the index dog was positive on the same sample occasion. Three contact dogs were consistently MRSP-negative. The data from whole genome sequencing showed similarities between isolates within each family group, indicating that MRSP was transmitted within each family. The results show that the risk of MRSP-colonization in dogs living with an MRSP-infected dog is reduced if the index dog becomes MRSP negative. All of the contact dogs will not carry MRSP continuously during the time the index dog is MRSP-positive. The information yielded from whole genome sequencing showed the methodology to be a promising additional tool in epidemiologic investigations of MRSP transmission." @default.
- W2321808643 created "2016-06-24" @default.
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- W2321808643 date "2016-06-01" @default.
- W2321808643 modified "2023-10-09" @default.
- W2321808643 title "Colonization with methicillin-resistant Staphylococcus pseudintermedius in multi-dog households: A longitudinal study using whole genome sequencing" @default.
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- W2321808643 doi "https://doi.org/10.1016/j.vetmic.2016.04.010" @default.
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