FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321811911> ?p ?o ?g. }

• W2321811911 endingPage "328" @default.
• W2321811911 startingPage "323" @default.
• W2321811911 abstract "A substrain of the senescence-accelerated mouse (SAM), the SAMP1 mouse, is an animal model for accelerated senescence including the age-related acceleration of both immunological dysfunction and hearing loss caused by the impairment of spiral ganglion cells. In the present study, we examine whether the accelerated presbycusis can be prevented by allogeneic BMT. Young SAMP1 (H-2k) mice were irradiated with 9 Gy and then reconstituted with bone marrow cells from normal BALB/c (H-2d) mice. Allogeneic BMT was found to prevent the development of immunological dysfunction, hearing loss, and apoptosis of spinal ganglion cells in SAMP1 mice. These findings indicate that some types of accelerated presbycusis do not result from defects in the cochlea, but do from defects in the hematopoietic stem cells (HSC) and immunocompetent cells derived from the HSC. If this is the case, either allogeneic BMT, which replaces abnormal HSC with normal HSC and reconstructs a normal immune system in the recipients, or autologous BMT using genetically modified bone marrow cells, could become a new strategy for the treatment of presbycusis. Bone Marrow Transplantation (2001) 28, 323–328." @default.
• W2321811911 created "2016-06-24" @default.
• W2321811911 creator A5014257346 @default.
• W2321811911 creator A5023690120 @default.
• W2321811911 creator A5062623525 @default.
• W2321811911 creator A5066379752 @default.
• W2321811911 creator A5073928383 @default.
• W2321811911 creator A5076608744 @default.
• W2321811911 creator A5080014403 @default.
• W2321811911 date "2001-08-01" @default.
• W2321811911 modified "2023-10-16" @default.
• W2321811911 title "Prevention of accelerated presbycusis by bone marrow transplantation in senescence-accelerated mice" @default.
• W2321811911 cites W1506053156 @default.
• W2321811911 cites W1557501694 @default.
• W2321811911 cites W1584484685 @default.
• W2321811911 cites W1966318223 @default.
• W2321811911 cites W1999630252 @default.
• W2321811911 cites W2009106926 @default.
• W2321811911 cites W2018062961 @default.
• W2321811911 cites W2023442607 @default.
• W2321811911 cites W2025958789 @default.
• W2321811911 cites W2027953622 @default.
• W2321811911 cites W2031375292 @default.
• W2321811911 cites W2039707427 @default.
• W2321811911 cites W2041281166 @default.
• W2321811911 cites W2050006450 @default.
• W2321811911 cites W2060446687 @default.
• W2321811911 cites W2080109656 @default.
• W2321811911 cites W2081802172 @default.
• W2321811911 cites W2087251720 @default.
• W2321811911 cites W2088038548 @default.
• W2321811911 cites W2102367498 @default.
• W2321811911 cites W2111790428 @default.
• W2321811911 cites W2138302361 @default.
• W2321811911 cites W2166023743 @default.
• W2321811911 cites W2316794082 @default.
• W2321811911 cites W2321057084 @default.
• W2321811911 cites W4206163632 @default.
• W2321811911 cites W88851328 @default.
• W2321811911 doi "https://doi.org/10.1038/sj.bmt.1703152" @default.
• W2321811911 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11571502" @default.
• W2321811911 hasPublicationYear "2001" @default.
• W2321811911 type Work @default.
• W2321811911 sameAs 2321811911 @default.
• W2321811911 citedByCount "23" @default.
• W2321811911 countsByYear W23218119112013 @default.
• W2321811911 countsByYear W23218119112014 @default.
• W2321811911 countsByYear W23218119112016 @default.
• W2321811911 countsByYear W23218119112019 @default.
• W2321811911 crossrefType "journal-article" @default.
• W2321811911 hasAuthorship W2321811911A5014257346 @default.
• W2321811911 hasAuthorship W2321811911A5023690120 @default.
• W2321811911 hasAuthorship W2321811911A5062623525 @default.
• W2321811911 hasAuthorship W2321811911A5066379752 @default.
• W2321811911 hasAuthorship W2321811911A5073928383 @default.
• W2321811911 hasAuthorship W2321811911A5076608744 @default.
• W2321811911 hasAuthorship W2321811911A5080014403 @default.
• W2321811911 hasBestOaLocation W23218119111 @default.
• W2321811911 hasConcept C105702510 @default.
• W2321811911 hasConcept C109159458 @default.
• W2321811911 hasConcept C126322002 @default.
• W2321811911 hasConcept C142724271 @default.
• W2321811911 hasConcept C203014093 @default.
• W2321811911 hasConcept C2779152698 @default.
• W2321811911 hasConcept C2779912225 @default.
• W2321811911 hasConcept C2780007613 @default.
• W2321811911 hasConcept C2780130748 @default.
• W2321811911 hasConcept C2780493683 @default.
• W2321811911 hasConcept C28328180 @default.
• W2321811911 hasConcept C2911091166 @default.
• W2321811911 hasConcept C522857546 @default.
• W2321811911 hasConcept C548259974 @default.
• W2321811911 hasConcept C71924100 @default.
• W2321811911 hasConcept C86803240 @default.
• W2321811911 hasConcept C95444343 @default.
• W2321811911 hasConceptScore W2321811911C105702510 @default.
• W2321811911 hasConceptScore W2321811911C109159458 @default.
• W2321811911 hasConceptScore W2321811911C126322002 @default.
• W2321811911 hasConceptScore W2321811911C142724271 @default.
• W2321811911 hasConceptScore W2321811911C203014093 @default.
• W2321811911 hasConceptScore W2321811911C2779152698 @default.
• W2321811911 hasConceptScore W2321811911C2779912225 @default.
• W2321811911 hasConceptScore W2321811911C2780007613 @default.
• W2321811911 hasConceptScore W2321811911C2780130748 @default.
• W2321811911 hasConceptScore W2321811911C2780493683 @default.
• W2321811911 hasConceptScore W2321811911C28328180 @default.
• W2321811911 hasConceptScore W2321811911C2911091166 @default.
• W2321811911 hasConceptScore W2321811911C522857546 @default.
• W2321811911 hasConceptScore W2321811911C548259974 @default.
• W2321811911 hasConceptScore W2321811911C71924100 @default.
• W2321811911 hasConceptScore W2321811911C86803240 @default.
• W2321811911 hasConceptScore W2321811911C95444343 @default.
• W2321811911 hasIssue "4" @default.
• W2321811911 hasLocation W23218119111 @default.
• W2321811911 hasLocation W23218119112 @default.
• W2321811911 hasOpenAccess W2321811911 @default.
• W2321811911 hasPrimaryLocation W23218119111 @default.
• W2321811911 hasRelatedWork W1979487491 @default.

• next