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- W2321813394 abstract "Phospholipase D from Streptomyces effectively catalyzed the transfer reaction of the phosphatidyl residue from 3-sn-phosphatidylcholine to the 5'-hydroxyl group of nuclesides in a two-phase system. Thus, a variety of 5'-(3-sn-phosphatidyl)nucleosides could be readily prepared in high yields by means of this reaction. Among them, phosphatidyl-FUR (3b), phosphatidyl-Ara FC (8b), and phoshatidyl-neplanocin A (12b) each produced a significant increase in the life span mice bearing i.p.-implanted P388 leukemia, being more effective than the parent nucleosides." @default.
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- W2321813394 date "1988-01-01" @default.
- W2321813394 modified "2023-10-12" @default.
- W2321813394 title "A facile enzymatic synthesis of 5'-(3-sn-phosphatidyl) nucleosides and their antileukemic activities." @default.
- W2321813394 doi "https://doi.org/10.1248/cpb.36.209" @default.
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