Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321819857> ?p ?o ?g. }
- W2321819857 endingPage "376" @default.
- W2321819857 startingPage "376" @default.
- W2321819857 abstract "Immune functions represented by equal CD4 counts before and after highly active antiretroviral therapy (i.e., pre- and post-HAART) in the same HIV-infected patients, were examined. Twelve HIV-infected patients were included. Patients had equal CD4 counts pre- and post-HAART and were studied on average 30 months pre-HAART and 17 months post-HAART. Post-HAART, CD8+ T cells expressed greater amounts of CD28 (p < .02), smaller amounts of CD38 (p < .02), and a reduced proportion of CD4+CD28+ T cells expressed CD38+ (p < .01). Proliferation increased (p < 10) in lymphocyte cell cultures stimulated with pokeweed mitogens or Candida, and was correlated to expression of CD28 on T cells (p < .02). The proportion of CD3-CD16-CD56+ natural killer (NK) cells increased (p < .05) and CD3-CD16+CD56- NK cells declined (p < .01). Production of interferon-gamma increased (p < .10). The number of naive and memory T cells, the non-major histocompatibility complex (non-MHC)-restricted and HIV-specific MHC-restricted cytotoxicity and the production of macrophage inflammatory protein-1gamma were unchanged. The finding of increased expression of CD28, correlating to increased proliferation capacity, and diminished expression of CD38 on T cells, indicates that following long-term HAART, repopulation occurs with less activated cells with increased proliferative capacity. This finding may be of clinical importance in considering risk and vulnerability for progression of opportunistic infections post-HAART." @default.
- W2321819857 created "2016-06-24" @default.
- W2321819857 creator A5016974789 @default.
- W2321819857 creator A5020698708 @default.
- W2321819857 creator A5048955821 @default.
- W2321819857 creator A5058825966 @default.
- W2321819857 creator A5074362044 @default.
- W2321819857 creator A5091020935 @default.
- W2321819857 date "2006-08-01" @default.
- W2321819857 modified "2023-10-10" @default.
- W2321819857 title "Immune Function and Phenotype Before and After Highly Active Antiretroviral Therapy" @default.
- W2321819857 cites W118686632 @default.
- W2321819857 cites W1481612531 @default.
- W2321819857 cites W1853823794 @default.
- W2321819857 cites W1967706218 @default.
- W2321819857 cites W1977775509 @default.
- W2321819857 cites W1982448824 @default.
- W2321819857 cites W1983933913 @default.
- W2321819857 cites W1988707875 @default.
- W2321819857 cites W1995237219 @default.
- W2321819857 cites W2010180443 @default.
- W2321819857 cites W2013403966 @default.
- W2321819857 cites W2014248122 @default.
- W2321819857 cites W2016458729 @default.
- W2321819857 cites W2020400573 @default.
- W2321819857 cites W2028346922 @default.
- W2321819857 cites W2029223860 @default.
- W2321819857 cites W2030055862 @default.
- W2321819857 cites W2030669661 @default.
- W2321819857 cites W2054522378 @default.
- W2321819857 cites W2056169141 @default.
- W2321819857 cites W2060976872 @default.
- W2321819857 cites W2064558165 @default.
- W2321819857 cites W2068480046 @default.
- W2321819857 cites W2075232100 @default.
- W2321819857 cites W2079846922 @default.
- W2321819857 cites W2123402662 @default.
- W2321819857 cites W2124846613 @default.
- W2321819857 cites W2158035002 @default.
- W2321819857 cites W2163345314 @default.
- W2321819857 cites W2327337490 @default.
- W2321819857 doi "https://doi.org/10.1097/01.pas.0000213299.11649.103" @default.
- W2321819857 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10458618" @default.
- W2321819857 hasPublicationYear "2006" @default.
- W2321819857 type Work @default.
- W2321819857 sameAs 2321819857 @default.
- W2321819857 citedByCount "22" @default.
- W2321819857 countsByYear W23218198572014 @default.
- W2321819857 countsByYear W23218198572019 @default.
- W2321819857 crossrefType "journal-article" @default.
- W2321819857 hasAuthorship W2321819857A5016974789 @default.
- W2321819857 hasAuthorship W2321819857A5020698708 @default.
- W2321819857 hasAuthorship W2321819857A5048955821 @default.
- W2321819857 hasAuthorship W2321819857A5058825966 @default.
- W2321819857 hasAuthorship W2321819857A5074362044 @default.
- W2321819857 hasAuthorship W2321819857A5091020935 @default.
- W2321819857 hasBestOaLocation W23218198571 @default.
- W2321819857 hasConcept C10205521 @default.
- W2321819857 hasConcept C114684123 @default.
- W2321819857 hasConcept C148125776 @default.
- W2321819857 hasConcept C154317977 @default.
- W2321819857 hasConcept C159912055 @default.
- W2321819857 hasConcept C167672396 @default.
- W2321819857 hasConcept C202751555 @default.
- W2321819857 hasConcept C203014093 @default.
- W2321819857 hasConcept C207936829 @default.
- W2321819857 hasConcept C2776090121 @default.
- W2321819857 hasConcept C28328180 @default.
- W2321819857 hasConcept C55493867 @default.
- W2321819857 hasConcept C86803240 @default.
- W2321819857 hasConcept C8891405 @default.
- W2321819857 hasConcept C95444343 @default.
- W2321819857 hasConceptScore W2321819857C10205521 @default.
- W2321819857 hasConceptScore W2321819857C114684123 @default.
- W2321819857 hasConceptScore W2321819857C148125776 @default.
- W2321819857 hasConceptScore W2321819857C154317977 @default.
- W2321819857 hasConceptScore W2321819857C159912055 @default.
- W2321819857 hasConceptScore W2321819857C167672396 @default.
- W2321819857 hasConceptScore W2321819857C202751555 @default.
- W2321819857 hasConceptScore W2321819857C203014093 @default.
- W2321819857 hasConceptScore W2321819857C207936829 @default.
- W2321819857 hasConceptScore W2321819857C2776090121 @default.
- W2321819857 hasConceptScore W2321819857C28328180 @default.
- W2321819857 hasConceptScore W2321819857C55493867 @default.
- W2321819857 hasConceptScore W2321819857C86803240 @default.
- W2321819857 hasConceptScore W2321819857C8891405 @default.
- W2321819857 hasConceptScore W2321819857C95444343 @default.
- W2321819857 hasIssue "5" @default.
- W2321819857 hasLocation W23218198571 @default.
- W2321819857 hasLocation W23218198572 @default.
- W2321819857 hasLocation W23218198573 @default.
- W2321819857 hasOpenAccess W2321819857 @default.
- W2321819857 hasPrimaryLocation W23218198571 @default.
- W2321819857 hasRelatedWork W127140033 @default.
- W2321819857 hasRelatedWork W1965096535 @default.
- W2321819857 hasRelatedWork W1992999743 @default.
- W2321819857 hasRelatedWork W2027999423 @default.
- W2321819857 hasRelatedWork W2041201944 @default.