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- W2321823462 abstract "In this study, we measured cytokines such as TNF-α in peripheral blood for 7 days after pancreatoduodenectomy or hepatic resection and investigated effects of preoperatively administered antibacterial agents on changes in these cytokines in terms of types of the agents. Agents and subjects investigated were imipenem/cilastatin sodium (IPM/CS) 1.0g/day in 16 cases; and ceftazidine (CAZ) 2.0g/day in 12 cases. All blood cytokines increased after the operations. Compared with CAZ patients group, the increase in TNF-α was significantly suppressed immediately (4 hours) after the operation, on the first and 7th postoperative days in the IPM/CS patients group. In short, it is suggested that postoperative changes in blood cytokines are affected by antibacterial agents, and the selection of antibacterial agents can be an important factor in patients undergoing highly invasive operations such as pancreatoduodenectomy and hepatic resection." @default.
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- W2321823462 date "2000-01-01" @default.
- W2321823462 modified "2023-09-27" @default.
- W2321823462 title "EFFECTS OF ANTIBACTERIAL AGENTS ON GENERAL RESPONSES OF BODY AFTER HIGHLY INVASIVE OPERATION" @default.
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- W2321823462 doi "https://doi.org/10.3919/jjsa.61.1377" @default.
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