Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321823768> ?p ?o ?g. }
- W2321823768 endingPage "108" @default.
- W2321823768 startingPage "100" @default.
- W2321823768 abstract "This review deals with the expectations of vitamin E ability of preventing or curing, as a potent antioxidant, alleged oxidative stress based ailments including cardiovascular disease, cancer, neurodegenerative diseases, cataracts, macular degeneration and more. The results obtained with clinical intervention studies have highly restricted the range of effectiveness of this vitamin. At the same time, new non-antioxidant mechanisms have been proposed. The new functions of vitamin E have been shown to affect cell signal transduction and gene expression, both in vitro and in vivo. Phosphorylation of vitamin E, which takes place in vivo, results in a molecule provided with functions that are in part stronger and in part different from those of the non-phosphorylate compound. The in vivo documented functions of vitamin E preventing the vitamin E deficiency ataxia (AVED), slowing down the progression of non-alcoholic steato-hepatitis (NASH), decreasing inflammation and potentiating the immune response are apparently based on these new molecular mechanisms. It should be stressed however that vitamin E, when present at higher concentrations in the body, should exert antioxidant properties to the extent that its chromanol ring is unprotected or un-esterified." @default.
- W2321823768 created "2016-06-24" @default.
- W2321823768 creator A5001814538 @default.
- W2321823768 creator A5030986047 @default.
- W2321823768 creator A5042840198 @default.
- W2321823768 creator A5055714543 @default.
- W2321823768 date "2016-04-01" @default.
- W2321823768 modified "2023-10-12" @default.
- W2321823768 title "The rise, the fall and the renaissance of vitamin E" @default.
- W2321823768 cites W1501007768 @default.
- W2321823768 cites W1504321233 @default.
- W2321823768 cites W1583483795 @default.
- W2321823768 cites W1819273906 @default.
- W2321823768 cites W1844380402 @default.
- W2321823768 cites W1905140162 @default.
- W2321823768 cites W1913115502 @default.
- W2321823768 cites W1914555825 @default.
- W2321823768 cites W1920804658 @default.
- W2321823768 cites W1921634414 @default.
- W2321823768 cites W1922087192 @default.
- W2321823768 cites W1971465028 @default.
- W2321823768 cites W1974468825 @default.
- W2321823768 cites W1975375149 @default.
- W2321823768 cites W1975515966 @default.
- W2321823768 cites W1976857952 @default.
- W2321823768 cites W1978177595 @default.
- W2321823768 cites W1979279652 @default.
- W2321823768 cites W1979726958 @default.
- W2321823768 cites W1980265413 @default.
- W2321823768 cites W1982233857 @default.
- W2321823768 cites W1983980559 @default.
- W2321823768 cites W1986072735 @default.
- W2321823768 cites W1987442873 @default.
- W2321823768 cites W1989803633 @default.
- W2321823768 cites W1990170694 @default.
- W2321823768 cites W1994217079 @default.
- W2321823768 cites W1999271515 @default.
- W2321823768 cites W1999492048 @default.
- W2321823768 cites W2002577841 @default.
- W2321823768 cites W2004637912 @default.
- W2321823768 cites W2006154113 @default.
- W2321823768 cites W2007196081 @default.
- W2321823768 cites W2007516026 @default.
- W2321823768 cites W2009275263 @default.
- W2321823768 cites W2009419950 @default.
- W2321823768 cites W2011336591 @default.
- W2321823768 cites W2011666969 @default.
- W2321823768 cites W2014027975 @default.
- W2321823768 cites W2014629593 @default.
- W2321823768 cites W2016665600 @default.
- W2321823768 cites W2018121042 @default.
- W2321823768 cites W2020398824 @default.
- W2321823768 cites W2020695495 @default.
- W2321823768 cites W2021451551 @default.
- W2321823768 cites W2021623951 @default.
- W2321823768 cites W2022340300 @default.
- W2321823768 cites W2022943997 @default.
- W2321823768 cites W2025830885 @default.
- W2321823768 cites W2027831359 @default.
- W2321823768 cites W2029143925 @default.
- W2321823768 cites W2033388875 @default.
- W2321823768 cites W2040071048 @default.
- W2321823768 cites W2040217192 @default.
- W2321823768 cites W2040923416 @default.
- W2321823768 cites W2042558624 @default.
- W2321823768 cites W2042888176 @default.
- W2321823768 cites W2043330098 @default.
- W2321823768 cites W2045871340 @default.
- W2321823768 cites W2046156506 @default.
- W2321823768 cites W2046561530 @default.
- W2321823768 cites W2047263121 @default.
- W2321823768 cites W2047550953 @default.
- W2321823768 cites W2050244960 @default.
- W2321823768 cites W2051150666 @default.
- W2321823768 cites W2054305537 @default.
- W2321823768 cites W2055897618 @default.
- W2321823768 cites W2057035976 @default.
- W2321823768 cites W2057149788 @default.
- W2321823768 cites W2058331808 @default.
- W2321823768 cites W2059933718 @default.
- W2321823768 cites W2060882276 @default.
- W2321823768 cites W2061242359 @default.
- W2321823768 cites W2061496053 @default.
- W2321823768 cites W2062812115 @default.
- W2321823768 cites W2065804275 @default.
- W2321823768 cites W2068754779 @default.
- W2321823768 cites W2069414414 @default.
- W2321823768 cites W2070162584 @default.
- W2321823768 cites W2071075050 @default.
- W2321823768 cites W2071433418 @default.
- W2321823768 cites W2073874316 @default.
- W2321823768 cites W2074612559 @default.
- W2321823768 cites W2078142642 @default.
- W2321823768 cites W2081764095 @default.
- W2321823768 cites W2087807294 @default.
- W2321823768 cites W2088390441 @default.
- W2321823768 cites W2094479423 @default.
- W2321823768 cites W2094846179 @default.