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- W2321835739 abstract "Valproate is very effective in anticonvulsant therapy. There is a variety of serious but rare side effects, e.g. gingival hyperplasia, a phenomenon commonly known under therapy with phenytoin, sometimes phenobarbital, primidon, cyclosporin or calcium channel blockers. We report on an 11 year old girl with a complex congenital brain anomality and a symptomatic epilepsy since age of 3 months, developing significant gingival hyperplasia under valproate monotherapy over 8 years. Discontinuing valproate for 6 months was stopped by increasing rate of seizures. Following giant gingival hyperplasia lead to breathing and swallowing problems. Operative correction was necessary, also permanent stop of potentially life-threatening valproate therapy." @default.
- W2321835739 created "2016-06-24" @default.
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- W2321835739 date "2006-12-01" @default.
- W2321835739 modified "2023-09-27" @default.
- W2321835739 title "Gingival hyperplasia in children treated with valproate: A case report" @default.
- W2321835739 doi "https://doi.org/10.1055/s-2006-974068" @default.
- W2321835739 hasPublicationYear "2006" @default.
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