FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321839851> ?p ?o ?g. }

• W2321839851 endingPage "e163" @default.
• W2321839851 startingPage "e163" @default.
• W2321839851 abstract "To evaluate the clinical relevance of myelin oligodendrocyte glycoprotein antibody (MOG-Ab) in a cohort of adults with inflammatory demyelinating disease (IDD) of the CNS.Live cell-based assays for MOG-Ab (IgG1 subset) and antibody to aquaporin-4 (AQP4-Ab) were performed in a cohort of 270 adult patients with IDD and 72 controls. Patients were first grouped by positive antibody result as MOG-Ab or AQP4-Ab, and the remainder were grouped by published diagnostic criteria.Seventeen patients with IDD (6.3%) had MOG-Abs and 49 patients (18.1%) had AQP4-Abs; none had both antibodies. The MOG-Ab patients predominantly manifested with isolated symptoms of optic neuritis (83%). One-third of these patients experienced relapses, which involved only the optic nerve, and all relapsed within 1 year of disease onset. At onset, MRI in the MOG-Ab group uniquely demonstrated perineural enhancement, extending to the soft tissues around the optic nerves (33%). Although about 30% of MOG-Ab patients had brain MRI lesions, they had fewer periventricular lesions than the 26 patients with relapsing-remitting multiple sclerosis (MS); none of these lesions were ovoid or perpendicular to the ventricle. Moreover, MOG-Ab patients did not meet the diagnostic criteria for definite neuromyelitis optica (NMO) and had less spinal cord involvement than the AQP4-Ab group. Four patients (23.5%) had poor visual outcomes (<0.2) or paraplegia.MOG-Abs may be a disease-specific biomarker in adult patients with IDD who have a disease distinct from NMO or MS. The radiologic as well as clinical manifestations of MOG-Ab patients can be useful in their differential diagnosis." @default.
• W2321839851 created "2016-06-24" @default.
• W2321839851 creator A5035290112 @default.
• W2321839851 creator A5038094544 @default.
• W2321839851 creator A5056964082 @default.
• W2321839851 creator A5060245852 @default.
• W2321839851 creator A5063171777 @default.
• W2321839851 creator A5066669488 @default.
• W2321839851 creator A5071797997 @default.
• W2321839851 creator A5088971868 @default.
• W2321839851 date "2015-10-15" @default.
• W2321839851 modified "2023-10-16" @default.
• W2321839851 title "Antibodies to MOG in adults with inflammatory demyelinating disease of the CNS" @default.
• W2321839851 cites W1811750802 @default.
• W2321839851 cites W1978631530 @default.
• W2321839851 cites W1994723621 @default.
• W2321839851 cites W2007502293 @default.
• W2321839851 cites W2026520986 @default.
• W2321839851 cites W2059045887 @default.
• W2321839851 cites W2069414099 @default.
• W2321839851 cites W2093292982 @default.
• W2321839851 cites W2093761772 @default.
• W2321839851 cites W2099833314 @default.
• W2321839851 cites W2103812851 @default.
• W2321839851 cites W2106131489 @default.
• W2321839851 cites W2107941546 @default.
• W2321839851 cites W2112165124 @default.
• W2321839851 cites W2120238028 @default.
• W2321839851 cites W2120340975 @default.
• W2321839851 cites W2122545833 @default.
• W2321839851 cites W2128597204 @default.
• W2321839851 cites W2136132690 @default.
• W2321839851 cites W2142577589 @default.
• W2321839851 cites W2154982729 @default.
• W2321839851 cites W2171753008 @default.
• W2321839851 cites W2244823862 @default.
• W2321839851 cites W2326911230 @default.
• W2321839851 cites W4255896580 @default.
• W2321839851 doi "https://doi.org/10.1212/nxi.0000000000000163" @default.
• W2321839851 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4608758" @default.
• W2321839851 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26516628" @default.
• W2321839851 hasPublicationYear "2015" @default.
• W2321839851 type Work @default.
• W2321839851 sameAs 2321839851 @default.
• W2321839851 citedByCount "191" @default.
• W2321839851 countsByYear W23218398512015 @default.
• W2321839851 countsByYear W23218398512016 @default.
• W2321839851 countsByYear W23218398512017 @default.
• W2321839851 countsByYear W23218398512018 @default.
• W2321839851 countsByYear W23218398512019 @default.
• W2321839851 countsByYear W23218398512020 @default.
• W2321839851 countsByYear W23218398512021 @default.
• W2321839851 countsByYear W23218398512022 @default.
• W2321839851 countsByYear W23218398512023 @default.
• W2321839851 crossrefType "journal-article" @default.
• W2321839851 hasAuthorship W2321839851A5035290112 @default.
• W2321839851 hasAuthorship W2321839851A5038094544 @default.
• W2321839851 hasAuthorship W2321839851A5056964082 @default.
• W2321839851 hasAuthorship W2321839851A5060245852 @default.
• W2321839851 hasAuthorship W2321839851A5063171777 @default.
• W2321839851 hasAuthorship W2321839851A5066669488 @default.
• W2321839851 hasAuthorship W2321839851A5071797997 @default.
• W2321839851 hasAuthorship W2321839851A5088971868 @default.
• W2321839851 hasBestOaLocation W23218398511 @default.
• W2321839851 hasConcept C118552586 @default.
• W2321839851 hasConcept C126322002 @default.
• W2321839851 hasConcept C142724271 @default.
• W2321839851 hasConcept C159654299 @default.
• W2321839851 hasConcept C203014093 @default.
• W2321839851 hasConcept C2776572573 @default.
• W2321839851 hasConcept C2777704947 @default.
• W2321839851 hasConcept C2778486448 @default.
• W2321839851 hasConcept C2778531937 @default.
• W2321839851 hasConcept C2779357208 @default.
• W2321839851 hasConcept C2780640218 @default.
• W2321839851 hasConcept C2780775167 @default.
• W2321839851 hasConcept C2781137167 @default.
• W2321839851 hasConcept C71924100 @default.
• W2321839851 hasConcept C72563966 @default.
• W2321839851 hasConceptScore W2321839851C118552586 @default.
• W2321839851 hasConceptScore W2321839851C126322002 @default.
• W2321839851 hasConceptScore W2321839851C142724271 @default.
• W2321839851 hasConceptScore W2321839851C159654299 @default.
• W2321839851 hasConceptScore W2321839851C203014093 @default.
• W2321839851 hasConceptScore W2321839851C2776572573 @default.
• W2321839851 hasConceptScore W2321839851C2777704947 @default.
• W2321839851 hasConceptScore W2321839851C2778486448 @default.
• W2321839851 hasConceptScore W2321839851C2778531937 @default.
• W2321839851 hasConceptScore W2321839851C2779357208 @default.
• W2321839851 hasConceptScore W2321839851C2780640218 @default.
• W2321839851 hasConceptScore W2321839851C2780775167 @default.
• W2321839851 hasConceptScore W2321839851C2781137167 @default.
• W2321839851 hasConceptScore W2321839851C71924100 @default.
• W2321839851 hasConceptScore W2321839851C72563966 @default.
• W2321839851 hasIssue "6" @default.
• W2321839851 hasLocation W23218398511 @default.
• W2321839851 hasLocation W23218398512 @default.
• W2321839851 hasLocation W23218398513 @default.

• next