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- W2321844353 abstract "A strain of Streptomyces hygroscopicus No. J296-21 (ATCC 39150) was found to produce a complex of new antibiotics, called inosamycins, which consisted of components A, B, C, D and E. They are novel aminocyclitol antibiotics structurally related to neomycin, paromomycin and ribostamycin. The antibiotic complex and each component of inosamycin exhibit a broad antibacterial spectrum but they are inactive against most of the aminoglycoside-resistant organisms. The antibacterial activity of inosamycin A, the major component of the complex, is comparable to that of neomycin but its acute toxicity is significantly lower (ca. 1/3) than that of neomycin." @default.
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- W2321844353 date "1985-01-01" @default.
- W2321844353 modified "2023-10-02" @default.
- W2321844353 title "Inosamycin, a complex of new aminoglycoside antibiotics. I. Production, isolation and properties." @default.
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- W2321844353 doi "https://doi.org/10.7164/antibiotics.38.1302" @default.
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