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- W2321847168 abstract "62歳,女性.左頚部腫瘤を主訴に来院.Virchowリンパ節と大動脈周囲リンパ節転移を伴う3型の直腸S状部低分化腺癌と診断された.CEAは45.8(正常値0.0～5.0)ng/ml.本例に,メトトレキセート(以下MTX)-5FU,5FU-ロイコボリン(以下LV)交互療法を3クール施行した.プロトコールは1コース56日間とし,前半4週に5FU急速静注のMTX-5FU交代療法を2回施行し,後半4週に5FU接続投与の5FU-LV療法を施行するものとした.2コース終了時において,原発巣は著効を示し,リンパ節転移は50%以上の縮小を認め,有効であった.CEAは9.5ng/mlへと低下した,この状態は4週間以上継続した.重篤な副作用は出現せず,performance statusは0のまま経過した.しかし,第3コースの半ばより,腫瘍は再度増大するようになり,全身状態の悪化とともに,治療開始から約9カ月後に死亡した." @default.
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- W2321847168 date "1998-01-01" @default.
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- W2321847168 title "A Case of Poorly-Differentiated Adenocarcinoma of Rectum Responding to MTX-5FU and 5FU-LV Alternate Therapy." @default.
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- W2321847168 doi "https://doi.org/10.3862/jcoloproctology.51.479" @default.
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