FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321856206> ?p ?o ?g. }

• W2321856206 abstract "s: Purpose: For patients with early stage lateralized head and neck cancer, unilateral radiotherapy has been shown a superior treatment than bilateral radiotherapy. Unilateral treatment not only maintains the same level of tumor control, it reduces treatment related toxicity. To take the advantage of treating a lateralized and smaller volume, radiotherapy has experi- enced evolution from mixed photon/electron fields, to wedge pair and IMRT treatment. The recent available proton treat- ment can offer further contralateral organ sparing but at a significantly higher financial cost, in addition to its technical complexities and limited accessibility. A new non-coplanar radiotherapy technique that is deliverable on existing C-arm linacs, term 4 , is in traduced in this article. Methods: Two patients with unilateral head and neck cancer were included in the planning study. The first patient was a post-surgical head-and-neck patient with a tumor involving posterior right maxillary sinus. The second patient had a pri- mary parotid tumor. A single-level 60 Gy was prescribed to the PTV. Three treatment plans were developed including volumetric modulated arc therapy (VMAT, clinically used) using 2 partial arcs, 4 plans using 6 MV non-coplanar beams, and a non-intensity-modulated 3-field proton plan. The 4 plans were created using an in-house optimization program. Both VMAT and the proton plans were generated on Eclipse (Varian). Results: All photon plans achieved 95% coverage of the PTV and less than 10% hot spots in the PTV. The proton plan showed greater dose heterogeneity in the PTV and greater high dose spillage to the surrounding normal tissue. For the first patient, comparison of the maximum doses between VMAT, 6 MV 4 and proton plans shows that for the contralat- eral cochlea, it was reduced from 15.6 to 4.6 and 0 Gy; the chiasm, it was from 31 to 10.6 and 7.2 Gy; for the contralateral lens, it was reduced from 6.2 to 1 and 1 Gy; for the contralateral optical nerve, it was reduced from 31.5 to 16.4 and 10.9 Gy; for the brain stem, it was reduced from 28.6 to 14.5 and 14.2 Gy. For the second patient, the same comparison shows that the spinal cord dose was reduced from 35.7 to 21.7 and 5 Gy, contralateral optical nerve dose was reduced from 35.1 to 16.3 and 8.7 Gy, contralateral eye dose was reduced from 12.1 to 7.5 and 0.1 Gy, contralateral lens dose was reduced from 5.5 to 3.1 and 0.1 Gy, contralateral cochlea dose was reduced from 24.6 to 8.52 and 0.05 Gy and contralateral pa- rotid dose was reduced from 14.5 to 5.11 and 0.15 Gy. Conclusion: The 4 plan's capacity to spare normal organs is benchmarked against the state of the art partial arc VMAT and proton plans. For well lateralized target in the case study, 4 plans showed remarkable potentials to further reduce distant organ doses compared to VMAT. While the level of distant organ sparing is not equivalent to proton therapy, 4 was able to attain the majority of the gains from using the proton therapy at the same time achieving superior PTV cover- age and proximal organ sparing." @default.
• W2321856206 created "2016-06-24" @default.
• W2321856206 creator A5009132246 @default.
• W2321856206 creator A5014037109 @default.
• W2321856206 creator A5024098067 @default.
• W2321856206 creator A5042160031 @default.
• W2321856206 creator A5051265222 @default.
• W2321856206 creator A5056932023 @default.
• W2321856206 creator A5062548316 @default.
• W2321856206 creator A5067633933 @default.
• W2321856206 creator A5091674984 @default.
• W2321856206 date "2015-04-06" @default.
• W2321856206 modified "2023-10-17" @default.
• W2321856206 title "Evolution of Ipsilateral Head and Neck Radiotherapy" @default.
• W2321856206 cites W1525220827 @default.
• W2321856206 cites W1594560149 @default.
• W2321856206 cites W1965894028 @default.
• W2321856206 cites W1975598755 @default.
• W2321856206 cites W1976792455 @default.
• W2321856206 cites W1979002500 @default.
• W2321856206 cites W1980647192 @default.
• W2321856206 cites W1982864028 @default.
• W2321856206 cites W1985507570 @default.
• W2321856206 cites W1995341036 @default.
• W2321856206 cites W2011307344 @default.
• W2321856206 cites W2018222378 @default.
• W2321856206 cites W2019570186 @default.
• W2321856206 cites W2029537185 @default.
• W2321856206 cites W2032305755 @default.
• W2321856206 cites W2046911659 @default.
• W2321856206 cites W2049769558 @default.
• W2321856206 cites W2053173679 @default.
• W2321856206 cites W2054183249 @default.
• W2321856206 cites W2059621826 @default.
• W2321856206 cites W2060863733 @default.
• W2321856206 cites W2061581169 @default.
• W2321856206 cites W2067751694 @default.
• W2321856206 cites W2071624787 @default.
• W2321856206 cites W2079494347 @default.
• W2321856206 cites W2080711481 @default.
• W2321856206 cites W2086263981 @default.
• W2321856206 cites W2086576321 @default.
• W2321856206 cites W2100371624 @default.
• W2321856206 cites W2129187957 @default.
• W2321856206 cites W2132109879 @default.
• W2321856206 cites W2144821424 @default.
• W2321856206 cites W2151157652 @default.
• W2321856206 cites W2166005406 @default.
• W2321856206 cites W2166163085 @default.
• W2321856206 cites W2170931246 @default.
• W2321856206 cites W2279957693 @default.
• W2321856206 doi "https://doi.org/10.2174/157339471004150407140632" @default.
• W2321856206 hasPublicationYear "2015" @default.
• W2321856206 type Work @default.
• W2321856206 sameAs 2321856206 @default.
• W2321856206 citedByCount "0" @default.
• W2321856206 crossrefType "journal-article" @default.
• W2321856206 hasAuthorship W2321856206A5009132246 @default.
• W2321856206 hasAuthorship W2321856206A5014037109 @default.
• W2321856206 hasAuthorship W2321856206A5024098067 @default.
• W2321856206 hasAuthorship W2321856206A5042160031 @default.
• W2321856206 hasAuthorship W2321856206A5051265222 @default.
• W2321856206 hasAuthorship W2321856206A5056932023 @default.
• W2321856206 hasAuthorship W2321856206A5062548316 @default.
• W2321856206 hasAuthorship W2321856206A5067633933 @default.
• W2321856206 hasAuthorship W2321856206A5091674984 @default.
• W2321856206 hasConcept C126838900 @default.
• W2321856206 hasConcept C141071460 @default.
• W2321856206 hasConcept C201645570 @default.
• W2321856206 hasConcept C2776530083 @default.
• W2321856206 hasConcept C2779244869 @default.
• W2321856206 hasConcept C2781266606 @default.
• W2321856206 hasConcept C2989005 @default.
• W2321856206 hasConcept C3018411727 @default.
• W2321856206 hasConcept C509974204 @default.
• W2321856206 hasConcept C71924100 @default.
• W2321856206 hasConceptScore W2321856206C126838900 @default.
• W2321856206 hasConceptScore W2321856206C141071460 @default.
• W2321856206 hasConceptScore W2321856206C201645570 @default.
• W2321856206 hasConceptScore W2321856206C2776530083 @default.
• W2321856206 hasConceptScore W2321856206C2779244869 @default.
• W2321856206 hasConceptScore W2321856206C2781266606 @default.
• W2321856206 hasConceptScore W2321856206C2989005 @default.
• W2321856206 hasConceptScore W2321856206C3018411727 @default.
• W2321856206 hasConceptScore W2321856206C509974204 @default.
• W2321856206 hasConceptScore W2321856206C71924100 @default.
• W2321856206 hasLocation W23218562061 @default.
• W2321856206 hasOpenAccess W2321856206 @default.
• W2321856206 hasPrimaryLocation W23218562061 @default.
• W2321856206 isParatext "false" @default.
• W2321856206 isRetracted "false" @default.
• W2321856206 magId "2321856206" @default.
• W2321856206 workType "article" @default.