Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321857158> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2321857158 endingPage "1330" @default.
- W2321857158 startingPage "1326" @default.
- W2321857158 abstract "The high prevalence of multidrug-resistant tuberculosis (MDR-TB) in the Philippines is a challenge for the National TB Programme.To assess patterns of drug resistance and screening outcomes among MDR-TB suspects evaluated from 2003 to 2008 at DOTS-Plus clinics in the Philippines.Descriptive study of 4897 consecutive patients with suspected MDR-TB.The median time from the first visit until a diagnosis of drug-resistant TB was 132 days (IQR 110-166 days). Among patients screened for MDR-TB, the most frequent resistance pattern among those previously treated in DOTS facilities was resistance to isoniazid (INH) and rifampicin (RMP). Resistance to INH+RMP plus fluoroquinolones was the most common pattern among those who had failed Category II treatment and patients treated by non-DOTS facilities. Among patients with MDR-TB, 57% ultimately received appropriate treatment with second-line drugs. The remaining 43% were lost to follow-up (25%), died (14%) or refused treatment (4%).Resistance to INH+RMP is the most frequent resistance pattern among patients referred from DOTS clinics in the Philippines for suspected MDR-TB. Initial use of standard regimens based on national survey data and quick uptake of new rapid molecular resistance tests may be useful to reduce diagnostic delays and expedite treatment for drug-resistant TB." @default.
- W2321857158 created "2016-06-24" @default.
- W2321857158 creator A5007362918 @default.
- W2321857158 creator A5033688269 @default.
- W2321857158 creator A5049474505 @default.
- W2321857158 creator A5053817241 @default.
- W2321857158 date "2012-10-01" @default.
- W2321857158 modified "2023-09-23" @default.
- W2321857158 title "Screening outcomes from patients with suspected multidrug-resistant tuberculosis: lessons learned in the Philippines" @default.
- W2321857158 doi "https://doi.org/10.5588/ijtld.12.0038" @default.
- W2321857158 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22863522" @default.
- W2321857158 hasPublicationYear "2012" @default.
- W2321857158 type Work @default.
- W2321857158 sameAs 2321857158 @default.
- W2321857158 citedByCount "7" @default.
- W2321857158 countsByYear W23218571582015 @default.
- W2321857158 countsByYear W23218571582017 @default.
- W2321857158 crossrefType "journal-article" @default.
- W2321857158 hasAuthorship W2321857158A5007362918 @default.
- W2321857158 hasAuthorship W2321857158A5033688269 @default.
- W2321857158 hasAuthorship W2321857158A5049474505 @default.
- W2321857158 hasAuthorship W2321857158A5053817241 @default.
- W2321857158 hasConcept C114851261 @default.
- W2321857158 hasConcept C126322002 @default.
- W2321857158 hasConcept C133936738 @default.
- W2321857158 hasConcept C142724271 @default.
- W2321857158 hasConcept C177713679 @default.
- W2321857158 hasConcept C187212893 @default.
- W2321857158 hasConcept C2776967927 @default.
- W2321857158 hasConcept C2777025531 @default.
- W2321857158 hasConcept C2777975735 @default.
- W2321857158 hasConcept C2778607973 @default.
- W2321857158 hasConcept C2781069245 @default.
- W2321857158 hasConcept C2909923361 @default.
- W2321857158 hasConcept C71924100 @default.
- W2321857158 hasConcept C86803240 @default.
- W2321857158 hasConcept C89423630 @default.
- W2321857158 hasConceptScore W2321857158C114851261 @default.
- W2321857158 hasConceptScore W2321857158C126322002 @default.
- W2321857158 hasConceptScore W2321857158C133936738 @default.
- W2321857158 hasConceptScore W2321857158C142724271 @default.
- W2321857158 hasConceptScore W2321857158C177713679 @default.
- W2321857158 hasConceptScore W2321857158C187212893 @default.
- W2321857158 hasConceptScore W2321857158C2776967927 @default.
- W2321857158 hasConceptScore W2321857158C2777025531 @default.
- W2321857158 hasConceptScore W2321857158C2777975735 @default.
- W2321857158 hasConceptScore W2321857158C2778607973 @default.
- W2321857158 hasConceptScore W2321857158C2781069245 @default.
- W2321857158 hasConceptScore W2321857158C2909923361 @default.
- W2321857158 hasConceptScore W2321857158C71924100 @default.
- W2321857158 hasConceptScore W2321857158C86803240 @default.
- W2321857158 hasConceptScore W2321857158C89423630 @default.
- W2321857158 hasIssue "10" @default.
- W2321857158 hasLocation W23218571581 @default.
- W2321857158 hasLocation W23218571582 @default.
- W2321857158 hasOpenAccess W2321857158 @default.
- W2321857158 hasPrimaryLocation W23218571581 @default.
- W2321857158 hasRelatedWork W2077780547 @default.
- W2321857158 hasRelatedWork W2115673253 @default.
- W2321857158 hasRelatedWork W2122261512 @default.
- W2321857158 hasRelatedWork W2189073339 @default.
- W2321857158 hasRelatedWork W2321815173 @default.
- W2321857158 hasRelatedWork W2321857158 @default.
- W2321857158 hasRelatedWork W2938138842 @default.
- W2321857158 hasRelatedWork W2942803432 @default.
- W2321857158 hasRelatedWork W4313441172 @default.
- W2321857158 hasRelatedWork W4323245276 @default.
- W2321857158 hasVolume "16" @default.
- W2321857158 isParatext "false" @default.
- W2321857158 isRetracted "false" @default.
- W2321857158 magId "2321857158" @default.
- W2321857158 workType "article" @default.