Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321858272> ?p ?o ?g. }
Showing items 1 to 51 of
51
with 100 items per page.
- W2321858272 abstract "Ferulic acid is a natural antioxidant and is found particularly in the cell walls of plants. Its esters have continued to receive great attention among researchers because of their wide range of therapeutic potentials. This realization has prompted us to synthesize rarely known long chain fatty acids derived esters of ferulic acid. Thus, our efforts have produced methyl 4-O-hexadecanyl ferulate, methyl 4-O-octadecanyl ferulate, methyl 4-O-octadec-Z-9-enyl ferulate and methyl 4-O-undec-11-enyl ferulate as fatty acid esters and methyl ester (9-COOCH3), using dicyclohexyl carbodiimide as an activating reagent in the presence of a catalytic amount of 4-dimethylaminopyridine. Reactions occurred at two reactive esterification sights, 9-COOH (methyl ferulate) and HO-C-4 (fatty acid esters) of methyl ferulate. Desired products were obtained in quantitative yields. The phenolic hydroxyl showed slow progress of esterification reactions and has taken longer reaction time to complete as compared to aliphatic alcohols. Two additional products in excellent yields, a dimer (4-O-9') and a 4-C-OCH3 were also prepared along with esters. The chemical structures of compounds have been elucidated by FTIR, 1H and 13C NMR and positive HRESI-MS spectroscopic data. The pharmacological (anti-oxidant and anti-cancer) studies have produced exciting results. The present research may help us to study structure-activity relationship. Fatty acid incorporated molecules of ferulic acid are rarely reported in literature." @default.
- W2321858272 created "2016-06-24" @default.
- W2321858272 creator A5005593074 @default.
- W2321858272 creator A5007599103 @default.
- W2321858272 creator A5060629917 @default.
- W2321858272 creator A5069069692 @default.
- W2321858272 creator A5087009051 @default.
- W2321858272 date "2012-03-07" @default.
- W2321858272 modified "2023-10-16" @default.
- W2321858272 title "Ferulic Acid Fatty Esters Synthesis: Physical and Biochemical Characteristics" @default.
- W2321858272 doi "https://doi.org/10.1055/s-0032-1307552" @default.
- W2321858272 hasPublicationYear "2012" @default.
- W2321858272 type Work @default.
- W2321858272 sameAs 2321858272 @default.
- W2321858272 citedByCount "1" @default.
- W2321858272 countsByYear W23218582722017 @default.
- W2321858272 crossrefType "journal-article" @default.
- W2321858272 hasAuthorship W2321858272A5005593074 @default.
- W2321858272 hasAuthorship W2321858272A5007599103 @default.
- W2321858272 hasAuthorship W2321858272A5060629917 @default.
- W2321858272 hasAuthorship W2321858272A5069069692 @default.
- W2321858272 hasAuthorship W2321858272A5087009051 @default.
- W2321858272 hasConcept C178790620 @default.
- W2321858272 hasConcept C185592680 @default.
- W2321858272 hasConcept C2780213334 @default.
- W2321858272 hasConcept C543025807 @default.
- W2321858272 hasConcept C55493867 @default.
- W2321858272 hasConceptScore W2321858272C178790620 @default.
- W2321858272 hasConceptScore W2321858272C185592680 @default.
- W2321858272 hasConceptScore W2321858272C2780213334 @default.
- W2321858272 hasConceptScore W2321858272C543025807 @default.
- W2321858272 hasConceptScore W2321858272C55493867 @default.
- W2321858272 hasIssue "05" @default.
- W2321858272 hasLocation W23218582721 @default.
- W2321858272 hasOpenAccess W2321858272 @default.
- W2321858272 hasPrimaryLocation W23218582721 @default.
- W2321858272 hasRelatedWork W132478626 @default.
- W2321858272 hasRelatedWork W1951753265 @default.
- W2321858272 hasRelatedWork W2009890993 @default.
- W2321858272 hasRelatedWork W2050108200 @default.
- W2321858272 hasRelatedWork W2088669026 @default.
- W2321858272 hasRelatedWork W2168611614 @default.
- W2321858272 hasRelatedWork W2317289584 @default.
- W2321858272 hasRelatedWork W2320547070 @default.
- W2321858272 hasRelatedWork W2330424792 @default.
- W2321858272 hasRelatedWork W2990096866 @default.
- W2321858272 hasVolume "78" @default.
- W2321858272 isParatext "false" @default.
- W2321858272 isRetracted "false" @default.
- W2321858272 magId "2321858272" @default.
- W2321858272 workType "article" @default.