Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321860022> ?p ?o ?g. }
- W2321860022 endingPage "245" @default.
- W2321860022 startingPage "233" @default.
- W2321860022 abstract "Introduction Bisphenol A (BPA) is an endocrine disruptor that is incorporated in many plastic industries worldwide. The exposure of humans to such substances starts from the fetal life to the postnatal life and extends throughout the life of the individual. Many agencies have raised warnings against the excessive use of such substances. Aim of work The present study was designed to evaluate the biochemical and histological changes induced by BPA in the testis of adult male albino rats and to detect the ability of self-regeneration after stoppage. Materials and methods Thirty-two adult male albino rats were used. The rats were divided equally into four groups (eight animals each). Groups I and II were used as negative and positive control groups, respectively. Rats of group III were given an oral dose of 50 mg/kg of BPA per day for 8 weeks. In group IV, the rats were treated in the same manner as in group III and then left without treatment for 4 weeks for recovery. At the time of sacrifice, all rats were anesthetized with ether, and blood samples were collected for estimation of testosterone. The testes were dissected out and processed for testicular malondialdehyde and glutathione measurement and light and electron microscopic examination. The diameter and epithelial height of the seminiferous tubules were estimated morphometrically and statistically analyzed. Results Biochemical results of the BPA-treated group (group III) revealed testicular affection with oxidative stress. Testes of this group showed many distorted seminiferous tubules lined by disorganized epithelium and separated with wide interstitium containing congested blood vessels. Apoptotic nuclei of some spermatids and intercellular spaces were also seen. There was a decrease in estrogen receptors. Statistical analysis of epithelial height and tubular diameter confirmed the results. However, in the recovery group (group IV), the histological and the biochemical changes were reduced but did not return to normal. Conclusion These results demonstrated that BPA had deleterious effects on the testis with some sort of self-recovery after stoppage." @default.
- W2321860022 created "2016-06-24" @default.
- W2321860022 creator A5045071054 @default.
- W2321860022 creator A5070340155 @default.
- W2321860022 date "2013-03-01" @default.
- W2321860022 modified "2023-10-13" @default.
- W2321860022 title "Testicular toxic changes induced by bisphenol A in adult albino rats" @default.
- W2321860022 cites W1971500946 @default.
- W2321860022 cites W1989755492 @default.
- W2321860022 cites W1991408409 @default.
- W2321860022 cites W2004056696 @default.
- W2321860022 cites W2006370393 @default.
- W2321860022 cites W2014210815 @default.
- W2321860022 cites W2020354530 @default.
- W2321860022 cites W2021792452 @default.
- W2321860022 cites W2022932571 @default.
- W2321860022 cites W2030823049 @default.
- W2321860022 cites W2032655535 @default.
- W2321860022 cites W2037738193 @default.
- W2321860022 cites W2038919867 @default.
- W2321860022 cites W2040074963 @default.
- W2321860022 cites W2041719197 @default.
- W2321860022 cites W2052377098 @default.
- W2321860022 cites W2056740995 @default.
- W2321860022 cites W2059110340 @default.
- W2321860022 cites W2065707820 @default.
- W2321860022 cites W2070215489 @default.
- W2321860022 cites W2070913019 @default.
- W2321860022 cites W2072007513 @default.
- W2321860022 cites W2079331135 @default.
- W2321860022 cites W2081746977 @default.
- W2321860022 cites W2082855416 @default.
- W2321860022 cites W2085192148 @default.
- W2321860022 cites W2085470067 @default.
- W2321860022 cites W2086542547 @default.
- W2321860022 cites W2086865501 @default.
- W2321860022 cites W2092552412 @default.
- W2321860022 cites W2108900261 @default.
- W2321860022 cites W2114729638 @default.
- W2321860022 cites W2118345202 @default.
- W2321860022 cites W2135854123 @default.
- W2321860022 cites W2138484830 @default.
- W2321860022 cites W2154751407 @default.
- W2321860022 cites W2168148786 @default.
- W2321860022 cites W2338548210 @default.
- W2321860022 cites W4214683323 @default.
- W2321860022 cites W4231671322 @default.
- W2321860022 doi "https://doi.org/10.1097/01.ehx.0000426163.95597.40" @default.
- W2321860022 hasPublicationYear "2013" @default.
- W2321860022 type Work @default.
- W2321860022 sameAs 2321860022 @default.
- W2321860022 citedByCount "4" @default.
- W2321860022 countsByYear W23218600222019 @default.
- W2321860022 countsByYear W23218600222022 @default.
- W2321860022 countsByYear W23218600222023 @default.
- W2321860022 crossrefType "journal-article" @default.
- W2321860022 hasAuthorship W2321860022A5045071054 @default.
- W2321860022 hasAuthorship W2321860022A5070340155 @default.
- W2321860022 hasBestOaLocation W23218600221 @default.
- W2321860022 hasConcept C123765429 @default.
- W2321860022 hasConcept C126322002 @default.
- W2321860022 hasConcept C134018914 @default.
- W2321860022 hasConcept C166595027 @default.
- W2321860022 hasConcept C16685009 @default.
- W2321860022 hasConcept C178790620 @default.
- W2321860022 hasConcept C181199279 @default.
- W2321860022 hasConcept C185592680 @default.
- W2321860022 hasConcept C2776151105 @default.
- W2321860022 hasConcept C2778401633 @default.
- W2321860022 hasConcept C2779279991 @default.
- W2321860022 hasConcept C2779684741 @default.
- W2321860022 hasConcept C2780862370 @default.
- W2321860022 hasConcept C2992926266 @default.
- W2321860022 hasConcept C42407357 @default.
- W2321860022 hasConcept C46699223 @default.
- W2321860022 hasConcept C538909803 @default.
- W2321860022 hasConcept C55493867 @default.
- W2321860022 hasConcept C71315377 @default.
- W2321860022 hasConcept C71924100 @default.
- W2321860022 hasConcept C86803240 @default.
- W2321860022 hasConceptScore W2321860022C123765429 @default.
- W2321860022 hasConceptScore W2321860022C126322002 @default.
- W2321860022 hasConceptScore W2321860022C134018914 @default.
- W2321860022 hasConceptScore W2321860022C166595027 @default.
- W2321860022 hasConceptScore W2321860022C16685009 @default.
- W2321860022 hasConceptScore W2321860022C178790620 @default.
- W2321860022 hasConceptScore W2321860022C181199279 @default.
- W2321860022 hasConceptScore W2321860022C185592680 @default.
- W2321860022 hasConceptScore W2321860022C2776151105 @default.
- W2321860022 hasConceptScore W2321860022C2778401633 @default.
- W2321860022 hasConceptScore W2321860022C2779279991 @default.
- W2321860022 hasConceptScore W2321860022C2779684741 @default.
- W2321860022 hasConceptScore W2321860022C2780862370 @default.
- W2321860022 hasConceptScore W2321860022C2992926266 @default.
- W2321860022 hasConceptScore W2321860022C42407357 @default.
- W2321860022 hasConceptScore W2321860022C46699223 @default.
- W2321860022 hasConceptScore W2321860022C538909803 @default.
- W2321860022 hasConceptScore W2321860022C55493867 @default.