Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321867209> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2321867209 abstract "Background : Regulation of cell volume is one of the major physiologic functions in living cells. Intracellular calcium ion and cytoskeletal component of cell membrane play pivotal roles in cell volume regulation. The significance of astroglial cell swelling is in its relation to delayed and permanent neuronal death. The aim of the current study is therefore to elucidate the effect of propofol on the cell volume, [Ca2+]i and actin filaments in astroglial cells. Methods : Astroglial cell line U1242MG astrocytoma cells were used in vitro. To investigate the alterations of cell volume and [Ca2+]i by propofol, flow cytometry system was used. Actin filaments were determined by tetramethylrhodamine isothiocyanate (TRITC)-phalloidin staining. Results : Treatment with propofol 10μg/ml for 15 min or 2 h perfusion reduced significantly both cell volume and [Ca2+]i. Cell volume was reduced 3∼4% in either duration of perfusion with propofol. Decreases in [Ca2+]i level in the presence of propofol was duration-dependent. Fifteen min perfusion with propofol caused 5% decrease in [Ca2+]i, but 2 h perfusion decreased [Ca2+]i further to 10%. The changes of actin filaments after propofol treatment for 30 min were apparently observed under fluorescent microscope. Conclusions : Changes of cell volume, [Ca2+]i and actin filaments are occurred by propofol in astroglial cells. Rearrangement of actin filaments may be associated with volume changes by propofol in astroglial cells. (Korean J Anesthesiol 1999; 36: 863∼868)" @default.
- W2321867209 created "2016-06-24" @default.
- W2321867209 creator A5004529998 @default.
- W2321867209 creator A5046864039 @default.
- W2321867209 date "1999-01-01" @default.
- W2321867209 modified "2023-09-27" @default.
- W2321867209 title "Propofol Decreases Cell Volume and Intracellular Calcium, and Rearranges Actin Filaments in Astroglial Cells" @default.
- W2321867209 doi "https://doi.org/10.4097/kjae.1999.36.5.863" @default.
- W2321867209 hasPublicationYear "1999" @default.
- W2321867209 type Work @default.
- W2321867209 sameAs 2321867209 @default.
- W2321867209 citedByCount "0" @default.
- W2321867209 crossrefType "journal-article" @default.
- W2321867209 hasAuthorship W2321867209A5004529998 @default.
- W2321867209 hasAuthorship W2321867209A5046864039 @default.
- W2321867209 hasConcept C12554922 @default.
- W2321867209 hasConcept C125705527 @default.
- W2321867209 hasConcept C126322002 @default.
- W2321867209 hasConcept C142669718 @default.
- W2321867209 hasConcept C146957229 @default.
- W2321867209 hasConcept C1491633281 @default.
- W2321867209 hasConcept C181080969 @default.
- W2321867209 hasConcept C185592680 @default.
- W2321867209 hasConcept C2776277131 @default.
- W2321867209 hasConcept C55493867 @default.
- W2321867209 hasConcept C71924100 @default.
- W2321867209 hasConcept C79879829 @default.
- W2321867209 hasConcept C86803240 @default.
- W2321867209 hasConcept C95444343 @default.
- W2321867209 hasConcept C98274493 @default.
- W2321867209 hasConceptScore W2321867209C12554922 @default.
- W2321867209 hasConceptScore W2321867209C125705527 @default.
- W2321867209 hasConceptScore W2321867209C126322002 @default.
- W2321867209 hasConceptScore W2321867209C142669718 @default.
- W2321867209 hasConceptScore W2321867209C146957229 @default.
- W2321867209 hasConceptScore W2321867209C1491633281 @default.
- W2321867209 hasConceptScore W2321867209C181080969 @default.
- W2321867209 hasConceptScore W2321867209C185592680 @default.
- W2321867209 hasConceptScore W2321867209C2776277131 @default.
- W2321867209 hasConceptScore W2321867209C55493867 @default.
- W2321867209 hasConceptScore W2321867209C71924100 @default.
- W2321867209 hasConceptScore W2321867209C79879829 @default.
- W2321867209 hasConceptScore W2321867209C86803240 @default.
- W2321867209 hasConceptScore W2321867209C95444343 @default.
- W2321867209 hasConceptScore W2321867209C98274493 @default.
- W2321867209 hasLocation W23218672091 @default.
- W2321867209 hasOpenAccess W2321867209 @default.
- W2321867209 hasPrimaryLocation W23218672091 @default.
- W2321867209 hasRelatedWork W1528106949 @default.
- W2321867209 hasRelatedWork W1581690915 @default.
- W2321867209 hasRelatedWork W1969895579 @default.
- W2321867209 hasRelatedWork W1984538941 @default.
- W2321867209 hasRelatedWork W1992349363 @default.
- W2321867209 hasRelatedWork W2007691921 @default.
- W2321867209 hasRelatedWork W2064033638 @default.
- W2321867209 hasRelatedWork W2069491024 @default.
- W2321867209 hasRelatedWork W2069898941 @default.
- W2321867209 hasRelatedWork W2074318844 @default.
- W2321867209 hasRelatedWork W2081756750 @default.
- W2321867209 hasRelatedWork W2168912331 @default.
- W2321867209 hasRelatedWork W2362354293 @default.
- W2321867209 hasRelatedWork W2400888006 @default.
- W2321867209 hasRelatedWork W2413193541 @default.
- W2321867209 hasRelatedWork W2473448248 @default.
- W2321867209 hasRelatedWork W2594726093 @default.
- W2321867209 hasRelatedWork W2607272301 @default.
- W2321867209 hasRelatedWork W2886882553 @default.
- W2321867209 hasRelatedWork W2274253833 @default.
- W2321867209 isParatext "false" @default.
- W2321867209 isRetracted "false" @default.
- W2321867209 magId "2321867209" @default.
- W2321867209 workType "article" @default.