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- W2321869835 abstract "The hepatoprotective effects of ethanol and ethyl acetate extracts of Gambia albidum were investigated on albino rats. The rats were grouped into four, A,B,C and D, in which A and B were positive and negative controls respectively. Hepatotoxicity was induced in group A with carbon tetrachloride only but not treated while it was not induced in (group B), the positive control. The hepatotoxicity induced in group C animals was treated with steam-borne ethanol extract while that of group D with ethyl acetate extract. The parameters measured were lipid peroxidation products, bilirubin, AST, protein, cholesterol. The mean lipid peroxidation values are 0.026 ± 0.0027, 0.031 ± 0.040, 0.029 ± 0.005 and 0.032 ± 0.002 for groups A, B, C and D respectively. The corresponding mean values for cholesterol were 3.91 ± 0.050, 0.42 ± 0.006, 0.39 ± 0.009, and 0.407 ± 0.015, 3.790 ± 0.235 for group A, B, C and D respectively. The corresponding values for bilirubin were 23.58 ±0.764, 16.50 ± 2.046, 21.92 ± 3.753 and 13.00 ± 0.750 for group A, B, C, and D respectively. The corresponding values of AST were 145 ± 1.071, 135.89 ± 1.614, 142.89 ± 11.042 and 119.33 ± 2.728 for group A,B,C and D respectively. Based on the above results, the two extracts, (ethanol and ethyl acetate) of Gambia albidum were moderately effective in providing protection against CCI4-induced hepatotoxicity." @default.
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- W2321869835 date "2014-01-01" @default.
- W2321869835 modified "2023-10-04" @default.
- W2321869835 title "Hepatoprotective Effects Of Gambia Albidum Bark Extract" @default.
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- W2321869835 doi "https://doi.org/10.9790/3008-09261822" @default.
- W2321869835 hasPublicationYear "2014" @default.
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