FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321870733> ?p ?o ?g. }

• W2321870733 endingPage "652" @default.
• W2321870733 startingPage "642" @default.
• W2321870733 abstract "Background Collection and processing characteristics influencing quality of cord blood (CB) units play an essential role to cord blood banks (CBBs). At many CBBs, volume reduction is performed using hydroxyethyl starch (HES) and the Sepax (Biosafe) automated cell processing system. Due to the withdrawal of HES from the European market, a validation of the nonHES protocol was performed. Methods This partially retrospective study identified CB characteristics such as gestational age and CB volume/cell count correlated with higher quality. For the nonHES validation, CB was analyzed for total nucleated cell (TNC), mononuclear cell (MNC) recovery, hematocrit (HCT) and colony-forming units (CFUs). Viabilities of CD34+ and CD45+ cells were determined by 7-aminoactinomycin D (7-AAD) and AnnexinV (AnnV) staining and compared for 21 mL and 42 mL buffy coat (BC) samples applying the HES/nonHES protocol. Results Factors affecting the potency of CB transplants were the gestational age and the volume reduction to a defined BC volume. High initial cell counts and CB volumes correlated negatively with post-processing TNC recovery for lower BC volumes. Post-processing HES and nonHES results were comparable, but nonHES revealed a significantly lower post-thaw recovery of viable CD34+ cells measured by 7-AAD/AnnV (21 mL: 45.4 ± 16.4%; 42 mL: 67.3 ± 14.5%) as compared with HES (21 mL: 72.7 ± 14.4%, P = 0.0164; 42 mL: 83.4 ± 14.7%, P = 0.0203). Discussion Due to the lower post-thaw CD34+ cell viability (AnnV−/7-AAD−) for nonHES samples, the use of HES is recommended, ideally combined with a high BC volume. The post-processing HCT has no statistically significant impact on the post-thaw CD34+ cell viability (AnnV−/7-AAD−)." @default.
• W2321870733 created "2016-06-24" @default.
• W2321870733 creator A5006877053 @default.
• W2321870733 creator A5076022552 @default.
• W2321870733 creator A5080246493 @default.
• W2321870733 creator A5086612032 @default.
• W2321870733 date "2016-05-01" @default.
• W2321870733 modified "2023-10-16" @default.
• W2321870733 title "Cord blood collection and processing with hydroxyethyl starch or non–hydroxyethyl starch" @default.
• W2321870733 cites W1485136427 @default.
• W2321870733 cites W1532162953 @default.
• W2321870733 cites W1839308135 @default.
• W2321870733 cites W1906638117 @default.
• W2321870733 cites W1965613868 @default.
• W2321870733 cites W1965743844 @default.
• W2321870733 cites W1991917280 @default.
• W2321870733 cites W1994891102 @default.
• W2321870733 cites W1997452013 @default.
• W2321870733 cites W2003970748 @default.
• W2321870733 cites W2009382439 @default.
• W2321870733 cites W2010055592 @default.
• W2321870733 cites W2011561948 @default.
• W2321870733 cites W2012784627 @default.
• W2321870733 cites W2026002902 @default.
• W2321870733 cites W2028552847 @default.
• W2321870733 cites W2037511867 @default.
• W2321870733 cites W2044840196 @default.
• W2321870733 cites W2048363418 @default.
• W2321870733 cites W2052319758 @default.
• W2321870733 cites W2052643123 @default.
• W2321870733 cites W2053822255 @default.
• W2321870733 cites W2054351679 @default.
• W2321870733 cites W2069209063 @default.
• W2321870733 cites W2078532650 @default.
• W2321870733 cites W2079339237 @default.
• W2321870733 cites W2080056706 @default.
• W2321870733 cites W2085516849 @default.
• W2321870733 cites W2086101504 @default.
• W2321870733 cites W2094243371 @default.
• W2321870733 cites W2099018713 @default.
• W2321870733 cites W2099847697 @default.
• W2321870733 cites W2103985859 @default.
• W2321870733 cites W2111255161 @default.
• W2321870733 cites W2123284794 @default.
• W2321870733 cites W2131703562 @default.
• W2321870733 cites W2138246948 @default.
• W2321870733 cites W2146924285 @default.
• W2321870733 cites W2330713242 @default.
• W2321870733 cites W4240479615 @default.
• W2321870733 cites W4245634061 @default.
• W2321870733 doi "https://doi.org/10.1016/j.jcyt.2016.02.003" @default.
• W2321870733 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27059201" @default.
• W2321870733 hasPublicationYear "2016" @default.
• W2321870733 type Work @default.
• W2321870733 sameAs 2321870733 @default.
• W2321870733 citedByCount "11" @default.
• W2321870733 countsByYear W23218707332017 @default.
• W2321870733 countsByYear W23218707332018 @default.
• W2321870733 countsByYear W23218707332019 @default.
• W2321870733 countsByYear W23218707332020 @default.
• W2321870733 countsByYear W23218707332021 @default.
• W2321870733 countsByYear W23218707332023 @default.
• W2321870733 crossrefType "journal-article" @default.
• W2321870733 hasAuthorship W2321870733A5006877053 @default.
• W2321870733 hasAuthorship W2321870733A5076022552 @default.
• W2321870733 hasAuthorship W2321870733A5080246493 @default.
• W2321870733 hasAuthorship W2321870733A5086612032 @default.
• W2321870733 hasConcept C10205521 @default.
• W2321870733 hasConcept C126322002 @default.
• W2321870733 hasConcept C137061746 @default.
• W2321870733 hasConcept C16685009 @default.
• W2321870733 hasConcept C185592680 @default.
• W2321870733 hasConcept C202751555 @default.
• W2321870733 hasConcept C203014093 @default.
• W2321870733 hasConcept C2778285947 @default.
• W2321870733 hasConcept C2779412105 @default.
• W2321870733 hasConcept C2780914630 @default.
• W2321870733 hasConcept C2780959883 @default.
• W2321870733 hasConcept C28328180 @default.
• W2321870733 hasConcept C55493867 @default.
• W2321870733 hasConcept C57992300 @default.
• W2321870733 hasConcept C71924100 @default.
• W2321870733 hasConcept C86803240 @default.
• W2321870733 hasConcept C95444343 @default.
• W2321870733 hasConceptScore W2321870733C10205521 @default.
• W2321870733 hasConceptScore W2321870733C126322002 @default.
• W2321870733 hasConceptScore W2321870733C137061746 @default.
• W2321870733 hasConceptScore W2321870733C16685009 @default.
• W2321870733 hasConceptScore W2321870733C185592680 @default.
• W2321870733 hasConceptScore W2321870733C202751555 @default.
• W2321870733 hasConceptScore W2321870733C203014093 @default.
• W2321870733 hasConceptScore W2321870733C2778285947 @default.
• W2321870733 hasConceptScore W2321870733C2779412105 @default.
• W2321870733 hasConceptScore W2321870733C2780914630 @default.
• W2321870733 hasConceptScore W2321870733C2780959883 @default.
• W2321870733 hasConceptScore W2321870733C28328180 @default.
• W2321870733 hasConceptScore W2321870733C55493867 @default.
• W2321870733 hasConceptScore W2321870733C57992300 @default.

• next