Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321880804> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2321880804 endingPage "108" @default.
- W2321880804 startingPage "103" @default.
- W2321880804 abstract "The present study was designed to evaluate whether microRNA-146a, as an NF-кB regulating factor and its adapter proteins (TRAF6 and IRAK1), are affected by diabetes in rat aorta.Male Wistar rats were randomly divided into control and diabetic groups (n=6 in each). Diabetes was induced by a single injection of streptozotocin (55 mg/kg; i.p.) in 12 h fasted rats. The gene expression of microRNA-146a, NF-κB, IRAK1, and TRAF6 were determined by real time PCR.The expression of microRNA-146a was down-regulated in diabetic aorta when compared with the control group (p<0.05). The mRNA expression levels of NF-кB, TRAF6 and IRAK1 also increased in the diabetic rat aorta when compared with their control counterparts (p<0.01 for all comparisons).These results suggest that down-regulation of microRNA-146a may lead to derangement in NF-кB negative feedback loop, propelling the aorta toward inflammation." @default.
- W2321880804 created "2016-06-24" @default.
- W2321880804 creator A5007106007 @default.
- W2321880804 creator A5026491392 @default.
- W2321880804 creator A5069331190 @default.
- W2321880804 creator A5074388802 @default.
- W2321880804 date "2014-01-01" @default.
- W2321880804 modified "2023-09-26" @default.
- W2321880804 title "MicroRNA-146a expression and its intervention in NF-кB signaling pathway in diabetic rat aorta" @default.
- W2321880804 doi "https://doi.org/10.4149/endo_2014_02_103" @default.
- W2321880804 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24824805" @default.
- W2321880804 hasPublicationYear "2014" @default.
- W2321880804 type Work @default.
- W2321880804 sameAs 2321880804 @default.
- W2321880804 citedByCount "12" @default.
- W2321880804 countsByYear W23218808042015 @default.
- W2321880804 countsByYear W23218808042017 @default.
- W2321880804 countsByYear W23218808042018 @default.
- W2321880804 countsByYear W23218808042019 @default.
- W2321880804 countsByYear W23218808042020 @default.
- W2321880804 countsByYear W23218808042021 @default.
- W2321880804 countsByYear W23218808042022 @default.
- W2321880804 crossrefType "journal-article" @default.
- W2321880804 hasAuthorship W2321880804A5007106007 @default.
- W2321880804 hasAuthorship W2321880804A5026491392 @default.
- W2321880804 hasAuthorship W2321880804A5069331190 @default.
- W2321880804 hasAuthorship W2321880804A5074388802 @default.
- W2321880804 hasConcept C104317684 @default.
- W2321880804 hasConcept C105580179 @default.
- W2321880804 hasConcept C126322002 @default.
- W2321880804 hasConcept C134018914 @default.
- W2321880804 hasConcept C145059251 @default.
- W2321880804 hasConcept C2776914184 @default.
- W2321880804 hasConcept C2777730290 @default.
- W2321880804 hasConcept C2779280383 @default.
- W2321880804 hasConcept C2779980429 @default.
- W2321880804 hasConcept C55493867 @default.
- W2321880804 hasConcept C555293320 @default.
- W2321880804 hasConcept C71924100 @default.
- W2321880804 hasConcept C86803240 @default.
- W2321880804 hasConceptScore W2321880804C104317684 @default.
- W2321880804 hasConceptScore W2321880804C105580179 @default.
- W2321880804 hasConceptScore W2321880804C126322002 @default.
- W2321880804 hasConceptScore W2321880804C134018914 @default.
- W2321880804 hasConceptScore W2321880804C145059251 @default.
- W2321880804 hasConceptScore W2321880804C2776914184 @default.
- W2321880804 hasConceptScore W2321880804C2777730290 @default.
- W2321880804 hasConceptScore W2321880804C2779280383 @default.
- W2321880804 hasConceptScore W2321880804C2779980429 @default.
- W2321880804 hasConceptScore W2321880804C55493867 @default.
- W2321880804 hasConceptScore W2321880804C555293320 @default.
- W2321880804 hasConceptScore W2321880804C71924100 @default.
- W2321880804 hasConceptScore W2321880804C86803240 @default.
- W2321880804 hasIssue "02" @default.
- W2321880804 hasLocation W23218808041 @default.
- W2321880804 hasLocation W23218808042 @default.
- W2321880804 hasOpenAccess W2321880804 @default.
- W2321880804 hasPrimaryLocation W23218808041 @default.
- W2321880804 hasRelatedWork W1995071802 @default.
- W2321880804 hasRelatedWork W2004012005 @default.
- W2321880804 hasRelatedWork W2011709829 @default.
- W2321880804 hasRelatedWork W2055342276 @default.
- W2321880804 hasRelatedWork W2064362993 @default.
- W2321880804 hasRelatedWork W2092993950 @default.
- W2321880804 hasRelatedWork W2094796798 @default.
- W2321880804 hasRelatedWork W2095626059 @default.
- W2321880804 hasRelatedWork W2140892006 @default.
- W2321880804 hasRelatedWork W2158125198 @default.
- W2321880804 hasVolume "48" @default.
- W2321880804 isParatext "false" @default.
- W2321880804 isRetracted "false" @default.
- W2321880804 magId "2321880804" @default.
- W2321880804 workType "article" @default.