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- W2321892158 abstract "Cell assemblies are thought to be the units of information representation in the brain, yet their detection from experimental data is arduous. Here, we propose to infer effective coupling networks and model distributions for the activity of simultaneously recorded neurons in prefrontal cortex, during the performance of a decision-making task, and during preceding and following sleep epochs. Our approach, inspired from statistical physics, allows us to define putative cell assemblies as the groups of co-activated neurons in the models of the three recorded epochs. It reveals the existence of task-related changes of the effective couplings between the sleep epochs. The assemblies which strongly coactivate during the task epoch are found to replay during subsequent sleep, in correspondence to the changes of the inferred network. Across sessions, a variety of different network scenarios is observed, providing insight in cell assembly formation and replay." @default.
- W2321892158 created "2016-06-24" @default.
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- W2321892158 date "2015-10-03" @default.
- W2321892158 modified "2023-09-24" @default.
- W2321892158 title "Inferred Model of the Prefrontal Cortex Activity Unveils Cell Assemblies and Memory Replay" @default.
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- W2321892158 doi "https://doi.org/10.1101/028316" @default.
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