Matches in SemOpenAlex for { <https://semopenalex.org/work/W2321992837> ?p ?o ?g. }
- W2321992837 endingPage "65" @default.
- W2321992837 startingPage "54" @default.
- W2321992837 abstract "Chronic hepatitis B is a global health problem that leads to development of various complications, such as cirrhosis, liver cancer, and liver failure requiring liver transplantation. The recurrence of hepatitis B virus (HBV) post-liver transplantation is a major cause of allograft dysfunction, cirrhosis of the allograft, and graft failure. Patients with high viral load at the time of transplantation, hepatitis B e antigen (HBeAg) positivity, or those with a history of anti-viral drug resistance are considered as high-risk for recurrent HBV post-liver transplantation, while patients with low viral load, including HBeAg negative status, acute liver failure, and hepatitis D virus (HDV) co-infection are considered to be at low-risk for recurrent HBV post-liver transplantation. Antivirals for patients awaiting liver transplantation(LT) cause suppression of HBV replication and reduce the risk of recurrent HBV infection of the allograft and, therefore, all HBV patients with decompensated cirrhosis should be treated with potent antivirals with high genetic barrier to resistance (entecavir or tenofovir) prior to liver transplantation. Prevention of post-liver transplantation recurrence should be done using a combination of hepatitis B immunoglobulin (HBIG) and antivirals in patients at high risk of recurrence. Low dose HBIG, HBIG-free protocols, and monoprophylaxis with high potency antivirals can still be considered in patients at low risk of recurrence. Even, marginal grafts from anti-HBc positive donors can be safely used in hepatitis B surface antigen (HBsAg) negative, preferably in anti-hepatitis B core (HBc)/anti-hepatitis B surface (HBs) positive recipients. In this article, we aim to review the mechanisms and risk factors of HBV recurrence post-LT in addition to the various treatment strategies proposed for the prevention of recurrent HBV infection" @default.
- W2321992837 created "2016-06-24" @default.
- W2321992837 creator A5041891746 @default.
- W2321992837 creator A5078805238 @default.
- W2321992837 date "2016-03-17" @default.
- W2321992837 modified "2023-09-27" @default.
- W2321992837 title "Prevention and Treatment of Recurrent Hepatitis B after Liver Transplantation" @default.
- W2321992837 cites W1487005018 @default.
- W2321992837 cites W1498734513 @default.
- W2321992837 cites W1520577186 @default.
- W2321992837 cites W1522175447 @default.
- W2321992837 cites W1550420486 @default.
- W2321992837 cites W1554720096 @default.
- W2321992837 cites W1565106849 @default.
- W2321992837 cites W1567510295 @default.
- W2321992837 cites W1590593271 @default.
- W2321992837 cites W1599988933 @default.
- W2321992837 cites W1793653203 @default.
- W2321992837 cites W1916536054 @default.
- W2321992837 cites W1926565507 @default.
- W2321992837 cites W1966233242 @default.
- W2321992837 cites W1971042391 @default.
- W2321992837 cites W1972629000 @default.
- W2321992837 cites W1972728638 @default.
- W2321992837 cites W1973392006 @default.
- W2321992837 cites W1974999149 @default.
- W2321992837 cites W1976192241 @default.
- W2321992837 cites W1983251878 @default.
- W2321992837 cites W1985423921 @default.
- W2321992837 cites W1986260234 @default.
- W2321992837 cites W1986388698 @default.
- W2321992837 cites W1993164142 @default.
- W2321992837 cites W1994485971 @default.
- W2321992837 cites W1994492381 @default.
- W2321992837 cites W1997047331 @default.
- W2321992837 cites W1997116657 @default.
- W2321992837 cites W1997270466 @default.
- W2321992837 cites W2002333870 @default.
- W2321992837 cites W2003692477 @default.
- W2321992837 cites W2006013394 @default.
- W2321992837 cites W2008818075 @default.
- W2321992837 cites W2010307710 @default.
- W2321992837 cites W2011760339 @default.
- W2321992837 cites W2012161811 @default.
- W2321992837 cites W2012621209 @default.
- W2321992837 cites W2013337360 @default.
- W2321992837 cites W2013568213 @default.
- W2321992837 cites W2014283640 @default.
- W2321992837 cites W2017560695 @default.
- W2321992837 cites W2023843484 @default.
- W2321992837 cites W2025096131 @default.
- W2321992837 cites W2027555120 @default.
- W2321992837 cites W2028215043 @default.
- W2321992837 cites W2028863333 @default.
- W2321992837 cites W2030000292 @default.
- W2321992837 cites W2030063899 @default.
- W2321992837 cites W2033239466 @default.
- W2321992837 cites W2037943801 @default.
- W2321992837 cites W2041661005 @default.
- W2321992837 cites W2042396550 @default.
- W2321992837 cites W2043017398 @default.
- W2321992837 cites W2043073732 @default.
- W2321992837 cites W2043837365 @default.
- W2321992837 cites W2044921992 @default.
- W2321992837 cites W2046798726 @default.
- W2321992837 cites W2046828081 @default.
- W2321992837 cites W2047015356 @default.
- W2321992837 cites W2053490914 @default.
- W2321992837 cites W2060231880 @default.
- W2321992837 cites W2060781265 @default.
- W2321992837 cites W2061594530 @default.
- W2321992837 cites W2063691198 @default.
- W2321992837 cites W2068100797 @default.
- W2321992837 cites W2068127052 @default.
- W2321992837 cites W2071904124 @default.
- W2321992837 cites W2077539073 @default.
- W2321992837 cites W2086867812 @default.
- W2321992837 cites W2088250981 @default.
- W2321992837 cites W2091910482 @default.
- W2321992837 cites W2093209276 @default.
- W2321992837 cites W2094491523 @default.
- W2321992837 cites W2096024044 @default.
- W2321992837 cites W2099933995 @default.
- W2321992837 cites W2101217776 @default.
- W2321992837 cites W2102266647 @default.
- W2321992837 cites W2104450067 @default.
- W2321992837 cites W2112436801 @default.
- W2321992837 cites W2115371558 @default.
- W2321992837 cites W2119446177 @default.
- W2321992837 cites W2119566778 @default.
- W2321992837 cites W2120426460 @default.
- W2321992837 cites W2124978182 @default.
- W2321992837 cites W2126145673 @default.
- W2321992837 cites W2126836514 @default.
- W2321992837 cites W2127889847 @default.
- W2321992837 cites W2129955924 @default.
- W2321992837 cites W2130207380 @default.
- W2321992837 cites W2130357985 @default.