Matches in SemOpenAlex for { <https://semopenalex.org/work/W2322005864> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2322005864 abstract "Solanum lycocarpum A. St.-Hil. (Solanaceae) are commonly used in traditional medicine for the treatment of diabetes and obesity, as well as for controlling cholesterol levels. Solasonine and solamargine are two major glycoalkaloids found in at least 100 Solanum species. In this sense, the aim of the present study was to evaluate the cytotoxic, genotoxic and antigenotoxic potential of S. lycocarpum fruits glycoalkaloid extract (SL), solamargine (SM) and solasonine (SS), in V79 cells. Cytotoxicity was evaluated by the colony forming assay. Genotoxic and antigenotoxic potential were evaluated by comet assay. Different concentrations of SL (4, 8, 16 and 32 µg/mL), SM (7.1µg/mL) and SS (14.4 µg/mL) were used for the evaluation of their genotoxic potential in V79 cells. In the antigenotoxicity assay, the different concentrations of SL, SM and SS were combined with methyl methanesulfonate (MMS). SL, SM and SS were cytotoxic at concentrations up to 32µg/mL, 7.1µg/mL and 14.4 µg/mL, respectively. The comet assay revealed that SL, SM and SS displayed no genotoxic activity, but they significantly reduced the extent of DNA damage induced by MMS." @default.
- W2322005864 created "2016-06-24" @default.
- W2322005864 creator A5019231918 @default.
- W2322005864 creator A5049115922 @default.
- W2322005864 creator A5049882661 @default.
- W2322005864 creator A5057149624 @default.
- W2322005864 creator A5086937956 @default.
- W2322005864 date "2012-07-01" @default.
- W2322005864 modified "2023-09-26" @default.
- W2322005864 title "Antigenotoxicity of Solanum lycocarpum glycoalkaloid extract and its majority compounds, solamargine and solasonine, in V79 cells" @default.
- W2322005864 doi "https://doi.org/10.1055/s-0032-1320384" @default.
- W2322005864 hasPublicationYear "2012" @default.
- W2322005864 type Work @default.
- W2322005864 sameAs 2322005864 @default.
- W2322005864 citedByCount "0" @default.
- W2322005864 crossrefType "journal-article" @default.
- W2322005864 hasAuthorship W2322005864A5019231918 @default.
- W2322005864 hasAuthorship W2322005864A5049115922 @default.
- W2322005864 hasAuthorship W2322005864A5049882661 @default.
- W2322005864 hasAuthorship W2322005864A5057149624 @default.
- W2322005864 hasAuthorship W2322005864A5086937956 @default.
- W2322005864 hasConcept C104317684 @default.
- W2322005864 hasConcept C109316439 @default.
- W2322005864 hasConcept C143425029 @default.
- W2322005864 hasConcept C185592680 @default.
- W2322005864 hasConcept C202751555 @default.
- W2322005864 hasConcept C2778761015 @default.
- W2322005864 hasConcept C2779589313 @default.
- W2322005864 hasConcept C2780358455 @default.
- W2322005864 hasConcept C33070731 @default.
- W2322005864 hasConcept C552990157 @default.
- W2322005864 hasConcept C55493867 @default.
- W2322005864 hasConcept C556039675 @default.
- W2322005864 hasConcept C71924100 @default.
- W2322005864 hasConcept C86803240 @default.
- W2322005864 hasConcept C98274493 @default.
- W2322005864 hasConceptScore W2322005864C104317684 @default.
- W2322005864 hasConceptScore W2322005864C109316439 @default.
- W2322005864 hasConceptScore W2322005864C143425029 @default.
- W2322005864 hasConceptScore W2322005864C185592680 @default.
- W2322005864 hasConceptScore W2322005864C202751555 @default.
- W2322005864 hasConceptScore W2322005864C2778761015 @default.
- W2322005864 hasConceptScore W2322005864C2779589313 @default.
- W2322005864 hasConceptScore W2322005864C2780358455 @default.
- W2322005864 hasConceptScore W2322005864C33070731 @default.
- W2322005864 hasConceptScore W2322005864C552990157 @default.
- W2322005864 hasConceptScore W2322005864C55493867 @default.
- W2322005864 hasConceptScore W2322005864C556039675 @default.
- W2322005864 hasConceptScore W2322005864C71924100 @default.
- W2322005864 hasConceptScore W2322005864C86803240 @default.
- W2322005864 hasConceptScore W2322005864C98274493 @default.
- W2322005864 hasIssue "11" @default.
- W2322005864 hasLocation W23220058641 @default.
- W2322005864 hasOpenAccess W2322005864 @default.
- W2322005864 hasPrimaryLocation W23220058641 @default.
- W2322005864 hasRelatedWork W1985240370 @default.
- W2322005864 hasRelatedWork W2002341164 @default.
- W2322005864 hasRelatedWork W2064307458 @default.
- W2322005864 hasRelatedWork W2094007812 @default.
- W2322005864 hasRelatedWork W2136013047 @default.
- W2322005864 hasRelatedWork W2137346717 @default.
- W2322005864 hasRelatedWork W2460663114 @default.
- W2322005864 hasRelatedWork W2838238898 @default.
- W2322005864 hasRelatedWork W3003257252 @default.
- W2322005864 hasRelatedWork W4283382418 @default.
- W2322005864 hasVolume "78" @default.
- W2322005864 isParatext "false" @default.
- W2322005864 isRetracted "false" @default.
- W2322005864 magId "2322005864" @default.
- W2322005864 workType "article" @default.