FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2322018130> ?p ?o ?g. }

• W2322018130 endingPage "e172" @default.
• W2322018130 startingPage "e168" @default.
• W2322018130 abstract "Background: The objective of this study was to estimate the efficacy of the neuraminidase (NA) inhibitors (NAIs) oseltamivir and zanamivir for decreasing viral load and to investigate whether NAI treatment decreases viral susceptibility to NAIs over time in children with influenza B virus infection. Methods: Of 27 patients with influenza B virus infection, 8 and 9 were treated with oseltamivir and zanamivir, respectively, whereas 10 received no NAI. Nasal aspiration samples, collected every morning until negative antigen results in 2 consecutive samples were observed, were subjected to viral load measurements by quantitative real-time reverse transcription polymerase chain reaction and viral susceptibility to NAI by NA inhibition assays. Results: Viral load decreased in both the oseltamivir and zanamivir groups by day 2 but increased in the no-NAI treatment group. Viral load in the oseltamivir and zanamivir groups on day 5 was 2.6% and 9.2% of that on day 0, respectively, whereas it was 26.4% in the no-NAI treatment group. Mean 50% inhibitory concentration (IC50) values of oseltamivir and zanamivir in the no-NAI treatment group were 5.0–6.6 and 1.3–1.8 nM, respectively. Mean IC50 values of oseltamivir and zanamivir in patients treated with oseltamivir and zanamivir were 3.9–8.8 and 1.3–1.8 nM, respectively. No major decrease in viral susceptibility to NAIs was observed during or after NAI treatment. Conclusions: NAI treatment was effective for inhibiting viral replication during the early days of illness and did not decrease viral susceptibility to NAIs in patients with influenza B virus infection." @default.
• W2322018130 created "2016-06-24" @default.
• W2322018130 creator A5016939457 @default.
• W2322018130 creator A5039224701 @default.
• W2322018130 creator A5044035162 @default.
• W2322018130 creator A5049495238 @default.
• W2322018130 creator A5067319030 @default.
• W2322018130 creator A5067319065 @default.
• W2322018130 creator A5071438977 @default.
• W2322018130 creator A5089549958 @default.
• W2322018130 date "2014-07-01" @default.
• W2322018130 modified "2023-09-25" @default.
• W2322018130 title "Sequential Influenza B Viral Load and Susceptibility in Children Treated With Oseltamivir and Zanamivir" @default.
• W2322018130 cites W1964972095 @default.
• W2322018130 cites W1972499074 @default.
• W2322018130 cites W1977775160 @default.
• W2322018130 cites W1987973326 @default.
• W2322018130 cites W2004554957 @default.
• W2322018130 cites W2010284659 @default.
• W2322018130 cites W2020899596 @default.
• W2322018130 cites W2026984266 @default.
• W2322018130 cites W2028849261 @default.
• W2322018130 cites W2034712058 @default.
• W2322018130 cites W2036015085 @default.
• W2322018130 cites W2066566514 @default.
• W2322018130 cites W2069233797 @default.
• W2322018130 cites W2082914311 @default.
• W2322018130 cites W2111005290 @default.
• W2322018130 cites W2111155300 @default.
• W2322018130 cites W2120850985 @default.
• W2322018130 cites W2121782636 @default.
• W2322018130 cites W2123034187 @default.
• W2322018130 cites W2124950712 @default.
• W2322018130 cites W2128060816 @default.
• W2322018130 cites W2130441728 @default.
• W2322018130 cites W2139841187 @default.
• W2322018130 cites W2144674187 @default.
• W2322018130 cites W2150047295 @default.
• W2322018130 cites W2153232301 @default.
• W2322018130 cites W2156231263 @default.
• W2322018130 cites W2157177671 @default.
• W2322018130 cites W2161420151 @default.
• W2322018130 cites W2163949383 @default.
• W2322018130 cites W2334261876 @default.
• W2322018130 doi "https://doi.org/10.1097/inf.0000000000000266" @default.
• W2322018130 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24445826" @default.
• W2322018130 hasPublicationYear "2014" @default.
• W2322018130 type Work @default.
• W2322018130 sameAs 2322018130 @default.
• W2322018130 citedByCount "7" @default.
• W2322018130 countsByYear W23220181302015 @default.
• W2322018130 countsByYear W23220181302017 @default.
• W2322018130 countsByYear W23220181302019 @default.
• W2322018130 countsByYear W23220181302022 @default.
• W2322018130 crossrefType "journal-article" @default.
• W2322018130 hasAuthorship W2322018130A5016939457 @default.
• W2322018130 hasAuthorship W2322018130A5039224701 @default.
• W2322018130 hasAuthorship W2322018130A5044035162 @default.
• W2322018130 hasAuthorship W2322018130A5049495238 @default.
• W2322018130 hasAuthorship W2322018130A5067319030 @default.
• W2322018130 hasAuthorship W2322018130A5067319065 @default.
• W2322018130 hasAuthorship W2322018130A5071438977 @default.
• W2322018130 hasAuthorship W2322018130A5089549958 @default.
• W2322018130 hasConcept C126322002 @default.
• W2322018130 hasConcept C134164806 @default.
• W2322018130 hasConcept C142462285 @default.
• W2322018130 hasConcept C159047783 @default.
• W2322018130 hasConcept C2522874641 @default.
• W2322018130 hasConcept C2777538117 @default.
• W2322018130 hasConcept C2779134260 @default.
• W2322018130 hasConcept C2780374985 @default.
• W2322018130 hasConcept C2781442963 @default.
• W2322018130 hasConcept C3008058167 @default.
• W2322018130 hasConcept C524204448 @default.
• W2322018130 hasConcept C71924100 @default.
• W2322018130 hasConceptScore W2322018130C126322002 @default.
• W2322018130 hasConceptScore W2322018130C134164806 @default.
• W2322018130 hasConceptScore W2322018130C142462285 @default.
• W2322018130 hasConceptScore W2322018130C159047783 @default.
• W2322018130 hasConceptScore W2322018130C2522874641 @default.
• W2322018130 hasConceptScore W2322018130C2777538117 @default.
• W2322018130 hasConceptScore W2322018130C2779134260 @default.
• W2322018130 hasConceptScore W2322018130C2780374985 @default.
• W2322018130 hasConceptScore W2322018130C2781442963 @default.
• W2322018130 hasConceptScore W2322018130C3008058167 @default.
• W2322018130 hasConceptScore W2322018130C524204448 @default.
• W2322018130 hasConceptScore W2322018130C71924100 @default.
• W2322018130 hasIssue "7" @default.
• W2322018130 hasLocation W23220181301 @default.
• W2322018130 hasLocation W23220181302 @default.
• W2322018130 hasOpenAccess W2322018130 @default.
• W2322018130 hasPrimaryLocation W23220181301 @default.
• W2322018130 hasRelatedWork W2035105077 @default.
• W2322018130 hasRelatedWork W2082914533 @default.
• W2322018130 hasRelatedWork W2099728935 @default.
• W2322018130 hasRelatedWork W2120554247 @default.
• W2322018130 hasRelatedWork W2128284760 @default.
• W2322018130 hasRelatedWork W2146569911 @default.

• next