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- W2322277717 abstract "I greatly appreciate the thoughtful comments from Drs Roessler and Zachenhofer. Their group has been a leader in the evaluation of methionine positron emission tomography and xenon-enhanced computed tomography in the delineation of anaplastic foci within gliomas. Their technique is much more widely available than 5-aminolevulinic acid and has been used at multiple centers with success. The novelty of the technique proposed by Widhalm et al1 is not the integration of metabolic imaging into neurosurgical image guidance, which has been well demonstrated by Dr Roessler. Rather, the real-time feedback that is provided by intraoperative fluorescence of high-grade areas is further confirmation to the operating surgeon that anaplastic foci are being sent for histopathological evaluation. Whether this information translates into meaningful clinical outcomes for patients with these tumors remains to be seen. Johnathan A. Engh Pittsburgh, Pennsylvania" @default.
- W2322277717 created "2016-06-24" @default.
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- W2322277717 date "2011-02-01" @default.
- W2322277717 modified "2023-10-16" @default.
- W2322277717 title "Anaplastic Foci Within Gliomas" @default.
- W2322277717 cites W2045165448 @default.
- W2322277717 doi "https://doi.org/10.1227/neu.0b013e31820417bd" @default.
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