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• W2322366918 abstract "OPEN ACCESSJuly 15, 2013The Making Evidence-Based Medicine Simple Series — Therapy Module Michael Mojica, MD Michael Mojica, MD New York University School of Medicine Google Scholar More articles by this author https://doi.org/10.15766/mep_2374-8265.9478 SectionsAboutAbstract ToolsDownload Citations ShareFacebookTwitterEmail AbstractAbstract Introduction: The Making Evidence Based Medicine Simple Series is an evidence-based clinical practice curriculum. It consists of six modules that review the articles types addressing the most common clinical questions (i.e., diagnosis, therapy, harm, prognosis, meta-analysis, and clinical decision rules). Each module reviews an article from the medical literature using the Users Guide to Medical Literature criteria for validity, results, and applicability. Each modules includes a PowerPoint presentation with a script, a video of the presentation with narration, a quiz with answers, tips for teaching the module, a blank review form, and a completed critical article review for the article reviewed in the module. Methods: The Therapy Module reviews the appraisal of the validity, results, and applicability of a randomized clinical trial of steroid therapy for mild croup. The study addresses the following clinical question: In children with mild croup in the emergency department, will oral dexamethasone when compared to placebo result in a reduction in unscheduled return visits? In addition, this module reviews the following critical appraisal skills: (1) differentiating between a superiority, non-inferiority, and equivalence analysis, (2) identifying the role of randomization, allocation concealment, and blinding in reducing bias, (3) distinguishing between an intention to treat and per protocol analysis, (4) calculating absolute risk, absolute risk reduction, and relative risk from a 2 × 2 table, (5) distinguishing between clinical and statistical significance, and (6) calculating/interpreting a number needed to treat. Results: Evaluations by course participants have been extremely positive. Participants often comment that they have finally grasped important content that they have previously struggled with. The materials have been particularly useful to those who are leading a teaching session. Feedback from a 2013 course for pediatric emergency medicine fellows indicated that 92% of participants felt the Therapy Module was “extremely helpful.” In addition, 100% of participants agreed or strongly agreed that the modules improved their ability to appraise an article, and their ability to conduct evidence-based clinical practice. One-hundred percent also agreed or strongly agreed that the precourse materials were useful. Discussion: The Making Evidence Based Medicine Simple Series is a well-received evidence based clinical practice curriculum and the Therapy Module is an effective component of the series that can be used independently or with the other modules. Educational Objectives By the end of this session, learners will be able to: Evaluate the validity, results, and applicability of a therapy article.Develop a “clinical bottom line” for a therapy article.Describe the steps in a randomized controlled trial.Differentiate analysis types (i.e., superiority, non-inferiority, and equivalence studies).Outline a therapy question in population/patient, intervention/indicator, comparator/control, and outcome format.Understand the validity criteria for a therapy study.Define randomization, allocation concealment, and blinding.Identify the effects of randomization, allocation concealment, and blinding on bias.Distinguish between an intention to treat and per protocol analysis.Calculate absolute risk, absolute risk reduction, and relative risk from a 2 × 2 table.Calculate relative risk reduction and understand its limitation.Distinguish between clinical and statistical significance.Interpret statistical significance from a confidence interval of an absolute risk reduction and relative risk.Understand the applicability criteria for a therapy study.Calculate and interpret a number needed to treat and number needed to harm.Create a clinical bottom line for a therapy study. Sign up for the latest publications from MedEdPORTAL Add your email below FILES INCLUDEDReferencesRelatedDetails FILES INCLUDED Included in this publication: Critical Appraisal Form - Therapy - Blank.doc Critical Appraisal From - Dexamethasone for Mild Croup.pdf EBM Teaching Tips - General Approach to the Modules.pdf EBM Teaching Tips - Therapy.pdf Instructor's Guide - MESS Curriculum - Overview.pdf Instructor's Guide - MESS Curriculum - Therapy Module.pdf Lecture Notes - Therapy.pdf Lecture Slides - Therapy.pdf Lecture Slides - Therapy.ppt QUIZ ANSWERS Therapy.pdf QUIZ Therapy.pdf Video Screencast - Therapy.mp4 To view all publication components, extract (i.e., unzip) them from the downloaded .zip file. Download editor’s noteThis publication may contain technology or a display format that is no longer in use. Related The Making Evidence-Based Medicine Simple Series — Diagnostic Testing Module The Making Evidence-Based Medicine Simple Series — Therapy Module The Making Evidence-Based Medicine Simple Series — Harm Module The Making Evidence-Based Medicine Simple Series — Prognosis Module The Making Evidence-Based Medicine Simple Series — Meta-analysis Module The Making Evidence-Based Medicine Simple Series - Clinical Decision Rule Module Copyright & Permissions© 2013 Mojica. This is an open-access publication distributed under the terms of the Creative Commons Attribution-NonCommercial license.KeywordsEvidence-Based Clinical PracticeMeta-AnalysisJournal ClubDiagnostic TestingClinical Prediction RuleHarmPrognosisClinical Decision RuleTherapyEvidence-Based Medicine Disclosures None to report. Funding/Support None to report. Loading ..." @default.
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• W2322366918 title "The Making Evidence-Based Medicine Simple Series — Therapy Module" @default.
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