FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2322436670> ?p ?o ?g. }

• W2322436670 abstract "Background: Invasive micropapillary carcinoma(IMPC) is a rare variant of invasive breast cancer that is associated with a high incidence of lymph node(LN) metastasis. But, the meaning of focal micropapillary component has not been fully elucidated. Methods: We retrospectively reviewed 88 invasive breast carcinoma cases with IMPC and focal micropapillary component. Results: Sixty-four cases had micropapillary component only in operative specimens, 18 cases had only in core-needle specimens, and 6 cases had in both. Sixteen were diagnosed as IMPC, and 72 cases had focal micropapillary component with other histological type of invasive breast carcinoma; 65 cases with invasive ductal carcinoma, 6 cases with mucinous carcinoma and one with metaplastic carcinoma. There was one male patient. Mean age was 56.5 years old. Median tumor size was 2.5 cm. Forty two (47.7%) cases were nuclear grade(NG)1, 16 (18.2%) were NG2 and 30 (34.1%) were NG3. Seventy eight cases (90%) were ERand/orPgR positive and 18.5% were HER2 positive. Six cases had distant metastasis at initial diagnosis. LN metastases were observed in 63.6% of all cases, and this high rate of LN metastasis could be seen even in small tumor group; 45.5% in cases with tumor equal or less than 2 cm. In the group of IMPC, 40.0% had LN metastasis, and 56.9% in cases with focal micropapillary component. There was no significant difference between IMPC and focal micropapillary component by univariate analysis(p = 0.055). Multivariate analysis of all cases showed that tumor size(>2cm)(p = 0.047), NG(1 vs 2&3, p = 0.017), and lymphatic invasion(p = 0.001) were significantly associated with LN metastasis. No significant difference between IMPC and focal micropapillary component was showed by multivariate analysis also (p = 0.60). Hormone receptor status or HER2 status were also not correlated(p = 0.92, p = 0.27 respectively). Among female patients without neoadjuvant chemotherapy, sentinel lymph node biopsy(SLNB) were underwent in 38 cases, and 16 cases (42.1%) had positive sentinel lymph node(SLN). Fourteen patients underwent additional axillary dissection and 7 cases (50%) had non-SLN metastases. Among patients with SLNB, 12 patients had micropapillary component in needle biopsy specimens, and 6 (50%) cases had positive SLN. Conclusion: Our data showed very high rate of LN metastasis in patients with micropapillary component, and this tendency still exists in cases with only focal micropapillary pattern. High positivity of SLNB was observed in these groups, and our data suggests that the findings of micropapillary component in CNB specimen could be used as a predictor of SLN metastasis. Citation Information: Cancer Res 2012;72(24 Suppl):Abstract nr P1-01-20." @default.
• W2322436670 created "2016-06-24" @default.
• W2322436670 creator A5005772091 @default.
• W2322436670 creator A5006840327 @default.
• W2322436670 creator A5024505043 @default.
• W2322436670 creator A5033974165 @default.
• W2322436670 creator A5036802092 @default.
• W2322436670 creator A5037644500 @default.
• W2322436670 creator A5039360739 @default.
• W2322436670 creator A5050439082 @default.
• W2322436670 creator A5052491173 @default.
• W2322436670 creator A5063310688 @default.
• W2322436670 creator A5064578609 @default.
• W2322436670 creator A5065213823 @default.
• W2322436670 creator A5072783490 @default.
• W2322436670 creator A5077699034 @default.
• W2322436670 creator A5085249791 @default.
• W2322436670 date "2012-12-15" @default.
• W2322436670 modified "2023-09-27" @default.
• W2322436670 title "Abstract P1-01-20: Clinicopathlogic Analysis of Invasive Breast Carcinoma with Micropapillary Component" @default.
• W2322436670 doi "https://doi.org/10.1158/0008-5472.sabcs12-p1-01-20" @default.
• W2322436670 hasPublicationYear "2012" @default.
• W2322436670 type Work @default.
• W2322436670 sameAs 2322436670 @default.
• W2322436670 citedByCount "0" @default.
• W2322436670 crossrefType "proceedings-article" @default.
• W2322436670 hasAuthorship W2322436670A5005772091 @default.
• W2322436670 hasAuthorship W2322436670A5006840327 @default.
• W2322436670 hasAuthorship W2322436670A5024505043 @default.
• W2322436670 hasAuthorship W2322436670A5033974165 @default.
• W2322436670 hasAuthorship W2322436670A5036802092 @default.
• W2322436670 hasAuthorship W2322436670A5037644500 @default.
• W2322436670 hasAuthorship W2322436670A5039360739 @default.
• W2322436670 hasAuthorship W2322436670A5050439082 @default.
• W2322436670 hasAuthorship W2322436670A5052491173 @default.
• W2322436670 hasAuthorship W2322436670A5063310688 @default.
• W2322436670 hasAuthorship W2322436670A5064578609 @default.
• W2322436670 hasAuthorship W2322436670A5065213823 @default.
• W2322436670 hasAuthorship W2322436670A5072783490 @default.
• W2322436670 hasAuthorship W2322436670A5077699034 @default.
• W2322436670 hasAuthorship W2322436670A5085249791 @default.
• W2322436670 hasConcept C121608353 @default.
• W2322436670 hasConcept C126322002 @default.
• W2322436670 hasConcept C142724271 @default.
• W2322436670 hasConcept C143998085 @default.
• W2322436670 hasConcept C144301174 @default.
• W2322436670 hasConcept C2776372563 @default.
• W2322436670 hasConcept C2777546739 @default.
• W2322436670 hasConcept C2779013556 @default.
• W2322436670 hasConcept C2780862961 @default.
• W2322436670 hasConcept C3018521938 @default.
• W2322436670 hasConcept C3020375857 @default.
• W2322436670 hasConcept C38180746 @default.
• W2322436670 hasConcept C530470458 @default.
• W2322436670 hasConcept C71924100 @default.
• W2322436670 hasConceptScore W2322436670C121608353 @default.
• W2322436670 hasConceptScore W2322436670C126322002 @default.
• W2322436670 hasConceptScore W2322436670C142724271 @default.
• W2322436670 hasConceptScore W2322436670C143998085 @default.
• W2322436670 hasConceptScore W2322436670C144301174 @default.
• W2322436670 hasConceptScore W2322436670C2776372563 @default.
• W2322436670 hasConceptScore W2322436670C2777546739 @default.
• W2322436670 hasConceptScore W2322436670C2779013556 @default.
• W2322436670 hasConceptScore W2322436670C2780862961 @default.
• W2322436670 hasConceptScore W2322436670C3018521938 @default.
• W2322436670 hasConceptScore W2322436670C3020375857 @default.
• W2322436670 hasConceptScore W2322436670C38180746 @default.
• W2322436670 hasConceptScore W2322436670C530470458 @default.
• W2322436670 hasConceptScore W2322436670C71924100 @default.
• W2322436670 hasLocation W23224366701 @default.
• W2322436670 hasOpenAccess W2322436670 @default.
• W2322436670 hasPrimaryLocation W23224366701 @default.
• W2322436670 hasRelatedWork W1805507973 @default.
• W2322436670 hasRelatedWork W1968856033 @default.
• W2322436670 hasRelatedWork W1981726950 @default.
• W2322436670 hasRelatedWork W2056551471 @default.
• W2322436670 hasRelatedWork W2079417588 @default.
• W2322436670 hasRelatedWork W2085072516 @default.
• W2322436670 hasRelatedWork W2134663318 @default.
• W2322436670 hasRelatedWork W2144209703 @default.
• W2322436670 hasRelatedWork W2353421525 @default.
• W2322436670 hasRelatedWork W2361165632 @default.
• W2322436670 hasRelatedWork W2373582262 @default.
• W2322436670 hasRelatedWork W2382572896 @default.
• W2322436670 hasRelatedWork W2594281481 @default.
• W2322436670 hasRelatedWork W2607149106 @default.
• W2322436670 hasRelatedWork W2786031626 @default.
• W2322436670 hasRelatedWork W2806779042 @default.
• W2322436670 hasRelatedWork W3029275198 @default.
• W2322436670 hasRelatedWork W3030678557 @default.
• W2322436670 hasRelatedWork W3159052842 @default.
• W2322436670 hasRelatedWork W2412110171 @default.
• W2322436670 isParatext "false" @default.
• W2322436670 isRetracted "false" @default.
• W2322436670 magId "2322436670" @default.
• W2322436670 workType "article" @default.