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- W2322730056 abstract "<h3>Aims</h3> To investigate the clearance of blood lactate level in neonates undergoing whole body cooling for hypoxic ischaemic encephalopathy (HIE) related to their outcome. <h3>Methods</h3> Retrospective case note review of infants receiving whole body cooling at a tertiary neonatal centre with outcome data enabling grouping into normal or abnormal neurological examination, or death, at follow up. Blood lactate measurements taken at 6, 12, 18, 24, 48, 72 and 96 hours were compared across the outcome groups. Data is given as median (± interquartile range) <h3>Results</h3> 61 infants were identified with birth weight 3.31 (2.77–3.55) kilogrammes, gestation 39 (38–40) completed weeks, ten minute Apgar score of 5 (2–6) and arterial cord pH 6.95 (6.82–7.08). 13 infants died, 14 had abnormal and 34 normal neurological follow up at last examination. Kruskal-Wallis test demonstrated significant differences in blood lactate between the three outcome groups at 6, 12, 18, 24, 48 and 72 hours: <h3>Conclusions</h3> In this preliminary study blood lactate measurement shows statistically significant differences for neonatal outcome in terms of death, abnormal or normal examination. This may aid prognostication in infants suffering HIE, and help determine further management." @default.
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- W2322730056 date "2013-04-01" @default.
- W2322730056 modified "2023-09-26" @default.
- W2322730056 title "PL.22 Lactate Clearance and Outcome in Neonates Cooled For Hypoxic Ischaemic Encephalopathy: Abstract PL.22 Table 1" @default.
- W2322730056 doi "https://doi.org/10.1136/archdischild-2013-303966.206" @default.
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