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• W2322851246 abstract "Purpose: It is well known that lower extremity (LE) deep vein thrombosis (DVT) is a common problem with potentially devastating results in patients undergoing major surgical procedures. But a few data are available on the incidence and prevention of LE DVT after kidney transplantation (KT). Most studies were designed retrospectively and came from Western countries. The aim of our study was to evaluate the incidence according to preventive methods of LE DVT within 1 month after KT in Korean. Methods: 187 consecutive patients were included during the period December 2009 to October 2011. These KT recipients were divided into two groups according to DVT prophylaxis. One group used graduated elastic stocking (GES) (n=93), the other group used pneumatic compression device (PCD) (N=94). In this study the frequency of LE DVT during the first 1 month after KT was evaluated using serial duplex ultrasound. The duplex ultrasound was performed on postoperative days (POD) 7, 14, 28. All patients were screened before KT for a hypercoagulable state by measuring the lupus anticoagulant, antiphospholipid antibody, hyperhomocysteinemia, protein C deficiency, protein S deficiency, antithrombin-III deficiency, Factor Va Leiden mutation and prothrombin gene 20210A mutation. At the end of surgery, closed suction drains were left in place until the drainage was less than 50 ml/day for two consecutive days. Results: LE DVT occurred in 4 patients (2.1%) during the first 4 weeks after KT. All DVT developed in GES group. None occurred in PCD group. In only one of the four was there any clinical evidence of a DVT and three patients were asymptomatic and the diagnoses were made during routine DU. All DVTs occurred on the side of the graft. The DVT developed a median time of 14 days (range 1-28 days) after kidney transplantation. Interestingly, Factor Va Leiden mutation and prothrombin gene 20210A mutation were not found in 187 consecutive patients recruited for the study and tested for genetic thrombophilia. Conclusion: The total incidence of DVT in this study was relatively lower than that of Western population and PCD could be reduced to some extent of the incidence of LE DVT compared with GES (p=0.058). And we could not found Factor Va Leiden mutation and prothrombin gene 20210A mutation in our study populations. These findings suggest that these inherited thrombophilic risk factors have to be considered as the main cause of a different incidence of DVT between different races." @default.
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• W2322851246 date "2012-11-01" @default.
• W2322851246 modified "2023-09-27" @default.
• W2322851246 title "Mechanical Thromboprophylaxis is Sufficient to Prevent Lower Extremity Deep Vein Thrombosis after Kidney Transplantation" @default.
• W2322851246 doi "https://doi.org/10.1097/00007890-201211271-01651" @default.
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