Matches in SemOpenAlex for { <https://semopenalex.org/work/W2322962512> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2322962512 endingPage "398" @default.
- W2322962512 startingPage "387" @default.
- W2322962512 abstract "According to the Institute of Medicine, the risk of clinically significant vitamin D deficiency increases at 25-hydroxyvitamin D levels below 20 ng/mL. By this standard, most cirrhotic hepatitis C virus- (HCV-) positive patients and many noncirrhotic patients are vitamin D-deficient. The high prevalence of vitamin D deficiency among HCV patients is a cause for concern for several specific reasons. Classic studies established the importance of vitamin D and calcium in maintaining bone. Vitamin D's beneficial effects on bone are likely to be vital for HCV-infected patients because these individuals have a high prevalence of low bone mineral density. Many pharmaceutical agents reduce bone density and exposure to these drugs may increase bone disease in HCV-positive patients. Bone loss occurs following liver transplantation and bone density is often low in patients with HIV/HCV co-infection who are on combination antiretroviral therapy. Some evidence suggests that ribavirin reduces bone density, underscoring the special need to monitor vitamin D in patients receiving HCV treatment and to prescribe supplements, as appropriate. In addition to its role in calcium metabolism, vitamin D is also an immune modulator that reduces inflammation while enhancing protective immune responses. Higher vitamin D levels are associated with less liver fibrosis and less inflammation in HCV patients. Recent studies show that low vitamin D levels are associated with treatment failure among HCV-infected patients receiving pegylated-interferon and ribavirin. If confirmed, these findings will provide an additional reason to ensure adequate levels of vitamin D. Information about how to monitor vitamin D status and how to use vitamin D supplements most effectively in HCV-infected patients is provided." @default.
- W2322962512 created "2016-06-24" @default.
- W2322962512 creator A5010225017 @default.
- W2322962512 creator A5014826725 @default.
- W2322962512 creator A5055503370 @default.
- W2322962512 date "2011-11-01" @default.
- W2322962512 modified "2023-10-06" @default.
- W2322962512 title "Classical and Emerging Roles of Vitamin D in Hepatitis C Virus Infection" @default.
- W2322962512 doi "https://doi.org/10.1055/s-0031-1297927" @default.
- W2322962512 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4107414" @default.
- W2322962512 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22189978" @default.
- W2322962512 hasPublicationYear "2011" @default.
- W2322962512 type Work @default.
- W2322962512 sameAs 2322962512 @default.
- W2322962512 citedByCount "58" @default.
- W2322962512 countsByYear W23229625122012 @default.
- W2322962512 countsByYear W23229625122013 @default.
- W2322962512 countsByYear W23229625122014 @default.
- W2322962512 countsByYear W23229625122015 @default.
- W2322962512 countsByYear W23229625122016 @default.
- W2322962512 countsByYear W23229625122017 @default.
- W2322962512 countsByYear W23229625122018 @default.
- W2322962512 countsByYear W23229625122019 @default.
- W2322962512 countsByYear W23229625122020 @default.
- W2322962512 countsByYear W23229625122021 @default.
- W2322962512 countsByYear W23229625122022 @default.
- W2322962512 crossrefType "journal-article" @default.
- W2322962512 hasAuthorship W2322962512A5010225017 @default.
- W2322962512 hasAuthorship W2322962512A5014826725 @default.
- W2322962512 hasAuthorship W2322962512A5055503370 @default.
- W2322962512 hasBestOaLocation W23229625122 @default.
- W2322962512 hasConcept C124490489 @default.
- W2322962512 hasConcept C126322002 @default.
- W2322962512 hasConcept C170033053 @default.
- W2322962512 hasConcept C203014093 @default.
- W2322962512 hasConcept C2522874641 @default.
- W2322962512 hasConcept C2776408679 @default.
- W2322962512 hasConcept C2776455275 @default.
- W2322962512 hasConcept C2776541429 @default.
- W2322962512 hasConcept C2776886416 @default.
- W2322962512 hasConcept C2776940978 @default.
- W2322962512 hasConcept C2779740938 @default.
- W2322962512 hasConcept C2780040827 @default.
- W2322962512 hasConcept C71924100 @default.
- W2322962512 hasConcept C8891405 @default.
- W2322962512 hasConcept C90924648 @default.
- W2322962512 hasConceptScore W2322962512C124490489 @default.
- W2322962512 hasConceptScore W2322962512C126322002 @default.
- W2322962512 hasConceptScore W2322962512C170033053 @default.
- W2322962512 hasConceptScore W2322962512C203014093 @default.
- W2322962512 hasConceptScore W2322962512C2522874641 @default.
- W2322962512 hasConceptScore W2322962512C2776408679 @default.
- W2322962512 hasConceptScore W2322962512C2776455275 @default.
- W2322962512 hasConceptScore W2322962512C2776541429 @default.
- W2322962512 hasConceptScore W2322962512C2776886416 @default.
- W2322962512 hasConceptScore W2322962512C2776940978 @default.
- W2322962512 hasConceptScore W2322962512C2779740938 @default.
- W2322962512 hasConceptScore W2322962512C2780040827 @default.
- W2322962512 hasConceptScore W2322962512C71924100 @default.
- W2322962512 hasConceptScore W2322962512C8891405 @default.
- W2322962512 hasConceptScore W2322962512C90924648 @default.
- W2322962512 hasIssue "04" @default.
- W2322962512 hasLocation W23229625121 @default.
- W2322962512 hasLocation W23229625122 @default.
- W2322962512 hasLocation W23229625123 @default.
- W2322962512 hasLocation W23229625124 @default.
- W2322962512 hasOpenAccess W2322962512 @default.
- W2322962512 hasPrimaryLocation W23229625121 @default.
- W2322962512 hasRelatedWork W1911438026 @default.
- W2322962512 hasRelatedWork W2033989269 @default.
- W2322962512 hasRelatedWork W2035258527 @default.
- W2322962512 hasRelatedWork W2037886755 @default.
- W2322962512 hasRelatedWork W2157642181 @default.
- W2322962512 hasRelatedWork W2322962512 @default.
- W2322962512 hasRelatedWork W2554990572 @default.
- W2322962512 hasRelatedWork W2570861097 @default.
- W2322962512 hasRelatedWork W2923640210 @default.
- W2322962512 hasRelatedWork W3043658442 @default.
- W2322962512 hasVolume "31" @default.
- W2322962512 isParatext "false" @default.
- W2322962512 isRetracted "false" @default.
- W2322962512 magId "2322962512" @default.
- W2322962512 workType "article" @default.