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- W2323057529 abstract "BACKGROUND: Fever is a common presenting symptom in paediatric outpatient practices and emergency rooms, particularly in children 99°F. Neonates with a clinical suspicion of sepsis were included in the study. A thorough history and physical examination and laboratory investigations - complete blood count, urine routine, C-reactive protein were retrieved from records. Cultures were obtained where indicated. OBSERVATIONS: A total of 44 children (18.3%) were diagnosed to have serious bacterial infection (SBI) out of the 240 febrile children studied during the 6 month period from Jan-June 2014. The incidence of reactive thrombocytosis was 20.7% and of these 28.6% was due to serious bacterial infection. The sensitivity and specificity of CRP in predicting SBI was 68.2% and 60.4% respectively considering a cut off value of >7mg/dl. Thrombocytosis i.e. platelet count >4lakh was more specific in diagnosing SBI with a sensitivity and specificity of 31.8% and 82.9% respectively. Leucocytosis ie total count >15000/mm3 also showed a higher specificity i.e., 63.9% than sensitivity i.e., 45.5%. Duration of pyrexia (>7days) had the maximum specificity of 91.7% thus having the best diagnostic accuracy among the variables studied i.e. 76.6%. Among the investigative methods platelet count had the best diagnostic accuracy i.e., 72.57%. CONCLUSION: Thrombocytosis was found to have the best diagnostic accuracy, among the investigative methods studied, in predicting serious bacterial infection (SBI)." @default.
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- W2323057529 date "2014-10-21" @default.
- W2323057529 modified "2023-10-16" @default.
- W2323057529 title "REACTIVE THROMBOCYTOSIS IN FEBRILE CHILDREN WITH SERIOUS BACTERIAL INFECTION" @default.
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- W2323057529 doi "https://doi.org/10.14260/jemds/2014/3662" @default.
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