Matches in SemOpenAlex for { <https://semopenalex.org/work/W2323083487> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2323083487 startingPage "84" @default.
- W2323083487 abstract "The aim of this study was to develop a fast releasing oral polymeric film, prepared using the solvent casting method, with good mechanical properties, instant disintegration and dissolution, an acceptable taste in the oral cavity. Levocetirizine dihydrochloride, an antihistamine, was incorporated to relieve the symptoms of allergic rhinitis. Four batches of films with drug were prepared using different combinations of polymers and plasticizers Eudragit® EPO, HPMC E 5 LV, and PVA were the selected polymers. Glycerin, dibutyl phthalate, propylene glycol, and PEG 400 were the selected plasticizers.The resultant films were evaluated for weight variation, assay, content uniformity, folding endurance, thickness, tensile strength, percent elongation, surface pH, in vitro disintegration and in vitro dissolution.The formulations from the preliminary trial were analyzed using Taguchi OA experimental design, which was applied to optimize the type of polymers, concentration of polymers, plasticizer, and sweetener based on their disintegration data at three different levels.The optimized films disintegrated in less than 30s, releasing 70-90% of drug within 2 mins.The percentage release varied with the type of polymer and concentration of polymer. The films made with EPO released 96% of drug in 2 mins, which was the best release among all." @default.
- W2323083487 created "2016-06-24" @default.
- W2323083487 creator A5037210361 @default.
- W2323083487 creator A5074290461 @default.
- W2323083487 creator A5084427767 @default.
- W2323083487 date "2011-01-01" @default.
- W2323083487 modified "2023-09-23" @default.
- W2323083487 title "Formulation development of fast releasing oral thin films of levocetrizine dihydrochloride with Eudragit® Epo and optimization through Taguchi orthogonal experimental design" @default.
- W2323083487 doi "https://doi.org/10.22377/ajp.v5i2.89" @default.
- W2323083487 hasPublicationYear "2011" @default.
- W2323083487 type Work @default.
- W2323083487 sameAs 2323083487 @default.
- W2323083487 citedByCount "8" @default.
- W2323083487 countsByYear W23230834872013 @default.
- W2323083487 countsByYear W23230834872014 @default.
- W2323083487 countsByYear W23230834872015 @default.
- W2323083487 countsByYear W23230834872016 @default.
- W2323083487 countsByYear W23230834872018 @default.
- W2323083487 countsByYear W23230834872019 @default.
- W2323083487 countsByYear W23230834872023 @default.
- W2323083487 crossrefType "journal-article" @default.
- W2323083487 hasAuthorship W2323083487A5037210361 @default.
- W2323083487 hasAuthorship W2323083487A5074290461 @default.
- W2323083487 hasAuthorship W2323083487A5084427767 @default.
- W2323083487 hasConcept C112950240 @default.
- W2323083487 hasConcept C127413603 @default.
- W2323083487 hasConcept C13965031 @default.
- W2323083487 hasConcept C159985019 @default.
- W2323083487 hasConcept C178790620 @default.
- W2323083487 hasConcept C185592680 @default.
- W2323083487 hasConcept C192562407 @default.
- W2323083487 hasConcept C2776035855 @default.
- W2323083487 hasConcept C2777937549 @default.
- W2323083487 hasConcept C2778551929 @default.
- W2323083487 hasConcept C42360764 @default.
- W2323083487 hasConcept C521977710 @default.
- W2323083487 hasConcept C58968531 @default.
- W2323083487 hasConcept C88380143 @default.
- W2323083487 hasConceptScore W2323083487C112950240 @default.
- W2323083487 hasConceptScore W2323083487C127413603 @default.
- W2323083487 hasConceptScore W2323083487C13965031 @default.
- W2323083487 hasConceptScore W2323083487C159985019 @default.
- W2323083487 hasConceptScore W2323083487C178790620 @default.
- W2323083487 hasConceptScore W2323083487C185592680 @default.
- W2323083487 hasConceptScore W2323083487C192562407 @default.
- W2323083487 hasConceptScore W2323083487C2776035855 @default.
- W2323083487 hasConceptScore W2323083487C2777937549 @default.
- W2323083487 hasConceptScore W2323083487C2778551929 @default.
- W2323083487 hasConceptScore W2323083487C42360764 @default.
- W2323083487 hasConceptScore W2323083487C521977710 @default.
- W2323083487 hasConceptScore W2323083487C58968531 @default.
- W2323083487 hasConceptScore W2323083487C88380143 @default.
- W2323083487 hasIssue "2" @default.
- W2323083487 hasLocation W23230834871 @default.
- W2323083487 hasOpenAccess W2323083487 @default.
- W2323083487 hasPrimaryLocation W23230834871 @default.
- W2323083487 hasRelatedWork W1553400323 @default.
- W2323083487 hasRelatedWork W1998349526 @default.
- W2323083487 hasRelatedWork W2027646141 @default.
- W2323083487 hasRelatedWork W2047667390 @default.
- W2323083487 hasRelatedWork W2061110091 @default.
- W2323083487 hasRelatedWork W2183230900 @default.
- W2323083487 hasRelatedWork W2183618524 @default.
- W2323083487 hasRelatedWork W2398988404 @default.
- W2323083487 hasRelatedWork W2731444193 @default.
- W2323083487 hasRelatedWork W2782859867 @default.
- W2323083487 hasRelatedWork W2886023486 @default.
- W2323083487 hasRelatedWork W2893390422 @default.
- W2323083487 hasRelatedWork W3026026829 @default.
- W2323083487 hasRelatedWork W3119488893 @default.
- W2323083487 hasRelatedWork W2184267647 @default.
- W2323083487 hasRelatedWork W2185984263 @default.
- W2323083487 hasRelatedWork W2186478426 @default.
- W2323083487 hasRelatedWork W2189098167 @default.
- W2323083487 hasRelatedWork W2556475911 @default.
- W2323083487 hasRelatedWork W2560738567 @default.
- W2323083487 hasVolume "5" @default.
- W2323083487 isParatext "false" @default.
- W2323083487 isRetracted "false" @default.
- W2323083487 magId "2323083487" @default.
- W2323083487 workType "article" @default.