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- W2323264003 abstract "Since neo-adjuvant therapy with intra-arterial infusion of CDDP/CBDCA and irradiation was introduced in our clinic, the cure rate of squamous cell carcinoma of the head and neck has improved greatly. However, not all patients have a good prognosis. We believe that one of the most important factors influencing patients' prognoses is the histological response to neo-adjuvant therapy. Seventy-five patients were divided into responders (47 patients) and nonresponders (28 patients) according to the histological findings of the resected materials. The former had a score of II B or more, and the latter II A or less according to Shimosato's classification.Though there was no significant difference between two groups with respect to T, N and stage classifications or tumor cell differentiation. The cumulative survival rate, calculated by the method of Kaplan-Meier was significantly higher in the responder group than in the nonresponder group (p<0.05, logrank test). The histological grading of malignancy before treatment was significantly lower in the responder group. The difference in the tumor-host relationship score between the groups was particularly large." @default.
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- W2323264003 title "Relationship between prognosis and histological findings of head and neck squamous cell carcinomas after neo-adjuvant therapy with intra-arterial infusion of platinum derivatives." @default.
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- W2323264003 doi "https://doi.org/10.5794/jjoms.42.889" @default.
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