Matches in SemOpenAlex for { <https://semopenalex.org/work/W2323376720> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2323376720 endingPage "1700" @default.
- W2323376720 startingPage "1693" @default.
- W2323376720 abstract "Abstract The fate of 14 C- and 35 S-ethylene dimethanesulphonate (EDS) has been studied in the mouse, rat, rabbit and monkey and compared with that of Myleran, a homologue of EDS. The rat and mouse excreted mainly unchanged 35 S-EDS, whereas from the rabbit and monkey only a minor proportion of the unhydrolysed ester was recovered in the urine. Methane sulphonic acid was the only radioactive urinary metabolite, and in this respect no species variation was encountered. In the rat 1,2- 14 C-EDS gave no evidence of simple hydrolysis since ethylene glycol was not found as a urinary metabolite. Expired radioactive carbon dioxide accounted for 5–8 per cent of the dose. Tissue distribution studies in the mouse show bone, blood and spleen have some selective uptake of EDS; the compound is only slowly cleared from these tissues. The relevance of the findings are discussed and related to comparable studies with Myleran in relation to the biological activity of both compounds." @default.
- W2323376720 created "2016-06-24" @default.
- W2323376720 creator A5004087630 @default.
- W2323376720 creator A5031640531 @default.
- W2323376720 creator A5079627447 @default.
- W2323376720 date "1969-07-01" @default.
- W2323376720 modified "2023-09-24" @default.
- W2323376720 title "Studies with alkylating esters—I" @default.
- W2323376720 cites W1480107011 @default.
- W2323376720 cites W1542337196 @default.
- W2323376720 cites W1570428701 @default.
- W2323376720 cites W1578025075 @default.
- W2323376720 cites W1579942930 @default.
- W2323376720 cites W1582893091 @default.
- W2323376720 cites W1583540134 @default.
- W2323376720 cites W1587407428 @default.
- W2323376720 cites W1652769732 @default.
- W2323376720 cites W17554010 @default.
- W2323376720 cites W1983654361 @default.
- W2323376720 cites W1984263373 @default.
- W2323376720 cites W1985695324 @default.
- W2323376720 cites W1991900815 @default.
- W2323376720 cites W2005761387 @default.
- W2323376720 cites W2006751059 @default.
- W2323376720 cites W2007926093 @default.
- W2323376720 cites W2010391082 @default.
- W2323376720 cites W2028691339 @default.
- W2323376720 cites W2034076905 @default.
- W2323376720 cites W2053747943 @default.
- W2323376720 cites W2056614075 @default.
- W2323376720 cites W2067410611 @default.
- W2323376720 cites W2070770688 @default.
- W2323376720 cites W2073210742 @default.
- W2323376720 cites W2091018157 @default.
- W2323376720 cites W2110477622 @default.
- W2323376720 cites W2142716991 @default.
- W2323376720 cites W2161040991 @default.
- W2323376720 cites W2220408282 @default.
- W2323376720 cites W2315102291 @default.
- W2323376720 cites W2321906419 @default.
- W2323376720 cites W2332464559 @default.
- W2323376720 cites W2410162638 @default.
- W2323376720 cites W48546832 @default.
- W2323376720 cites W655631690 @default.
- W2323376720 cites W2334552769 @default.
- W2323376720 doi "https://doi.org/10.1016/0006-2952(69)90158-0" @default.
- W2323376720 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4979843" @default.
- W2323376720 hasPublicationYear "1969" @default.
- W2323376720 type Work @default.
- W2323376720 sameAs 2323376720 @default.
- W2323376720 citedByCount "29" @default.
- W2323376720 countsByYear W23233767202014 @default.
- W2323376720 crossrefType "journal-article" @default.
- W2323376720 hasAuthorship W2323376720A5004087630 @default.
- W2323376720 hasAuthorship W2323376720A5031640531 @default.
- W2323376720 hasAuthorship W2323376720A5079627447 @default.
- W2323376720 hasConcept C185592680 @default.
- W2323376720 hasConcept C71924100 @default.
- W2323376720 hasConcept C98274493 @default.
- W2323376720 hasConceptScore W2323376720C185592680 @default.
- W2323376720 hasConceptScore W2323376720C71924100 @default.
- W2323376720 hasConceptScore W2323376720C98274493 @default.
- W2323376720 hasIssue "7" @default.
- W2323376720 hasLocation W23233767201 @default.
- W2323376720 hasLocation W23233767202 @default.
- W2323376720 hasOpenAccess W2323376720 @default.
- W2323376720 hasPrimaryLocation W23233767201 @default.
- W2323376720 hasRelatedWork W1531601525 @default.
- W2323376720 hasRelatedWork W1990781990 @default.
- W2323376720 hasRelatedWork W2314643286 @default.
- W2323376720 hasRelatedWork W2606768298 @default.
- W2323376720 hasRelatedWork W2606769243 @default.
- W2323376720 hasRelatedWork W2606837276 @default.
- W2323376720 hasRelatedWork W2748952813 @default.
- W2323376720 hasRelatedWork W2899084033 @default.
- W2323376720 hasRelatedWork W2948807893 @default.
- W2323376720 hasRelatedWork W2778153218 @default.
- W2323376720 hasVolume "18" @default.
- W2323376720 isParatext "false" @default.
- W2323376720 isRetracted "false" @default.
- W2323376720 magId "2323376720" @default.
- W2323376720 workType "article" @default.