Matches in SemOpenAlex for { <https://semopenalex.org/work/W2323692489> ?p ?o ?g. }
Showing items 1 to 86 of
86
with 100 items per page.
- W2323692489 endingPage "e58" @default.
- W2323692489 startingPage "e58" @default.
- W2323692489 abstract "Introduction: Administration of a diet rich in fructose initiates a series of metabolic events resulting in hypertriglyceridemia, hypertension and glucose intolerance. Objectives: The purpose of this study was to evaluate the role of the renin angiotensin system on cardiovascular function induced by fructose intake during 8 weeks. Desing and Methods: Weaned (21 days old) male Wistar rats (50-60 g) were divided in 2 groups and they were followed for 8 weeks: Control (CG) and Fructose (FG, 10% in drinking water). The participation of the renin-angiotensin system has been evaluated by receptor blockade AT1a with losartan (10 mg/kg iv) and by angiotensin-converting enzyme (ACE) in serum by fluorimetric measurements. Ganglionic blockade (hexamethonium, 20 mg/kg, iv) was used to determine vascular activity of sympathetic nervous system. Arterial pressure (AP) and heart rate (HR) were directly recorded using a data acquisition system (Windaq, 2 KHz) in conscious and awake rats. Results: FG showed an increase of mean AP (120±3.1 mmHg) when compared to CG (98±1.6 mmHg). No changes in heart rate were observed. Blocking with losartan showed an increased depressor response in FG (-18 ± 1.7 mm Hg) compared to the GC (-7 ± 1.5 mmHg) likewise after hexamethonium administration. ACE serum in FG (153±2,7 mU/mL) was higher than CG (103±14,3 mU/mL). Conclusions: In conclusion, these data suggest that metabolic changes induced by frutose-rich diet during life spam in rats are accompanied by hypertension associated with increase of renin angiotensin system and sympathetic overactivity." @default.
- W2323692489 created "2016-06-24" @default.
- W2323692489 creator A5007470819 @default.
- W2323692489 creator A5008620091 @default.
- W2323692489 creator A5028208939 @default.
- W2323692489 creator A5052570982 @default.
- W2323692489 creator A5068694729 @default.
- W2323692489 creator A5071569871 @default.
- W2323692489 creator A5080224808 @default.
- W2323692489 date "2012-09-01" @default.
- W2323692489 modified "2023-10-01" @default.
- W2323692489 title "196 EFFECTS ON SYMPATHETIC ACTIVITY AND RENIN ANGIOTENSIN SYNTEM IN EXPERIMENTAL METABOLIC SYNDROME MODEL" @default.
- W2323692489 doi "https://doi.org/10.1097/01.hjh.0000420023.15340.bb" @default.
- W2323692489 hasPublicationYear "2012" @default.
- W2323692489 type Work @default.
- W2323692489 sameAs 2323692489 @default.
- W2323692489 citedByCount "0" @default.
- W2323692489 crossrefType "journal-article" @default.
- W2323692489 hasAuthorship W2323692489A5007470819 @default.
- W2323692489 hasAuthorship W2323692489A5008620091 @default.
- W2323692489 hasAuthorship W2323692489A5028208939 @default.
- W2323692489 hasAuthorship W2323692489A5052570982 @default.
- W2323692489 hasAuthorship W2323692489A5068694729 @default.
- W2323692489 hasAuthorship W2323692489A5071569871 @default.
- W2323692489 hasAuthorship W2323692489A5080224808 @default.
- W2323692489 hasBestOaLocation W23236924891 @default.
- W2323692489 hasConcept C126322002 @default.
- W2323692489 hasConcept C134018914 @default.
- W2323692489 hasConcept C138976137 @default.
- W2323692489 hasConcept C170493617 @default.
- W2323692489 hasConcept C185592680 @default.
- W2323692489 hasConcept C198710026 @default.
- W2323692489 hasConcept C2775893369 @default.
- W2323692489 hasConcept C2776533406 @default.
- W2323692489 hasConcept C2776919658 @default.
- W2323692489 hasConcept C2776970464 @default.
- W2323692489 hasConcept C2777953023 @default.
- W2323692489 hasConcept C2778163477 @default.
- W2323692489 hasConcept C2778468042 @default.
- W2323692489 hasConcept C2778913445 @default.
- W2323692489 hasConcept C2780288358 @default.
- W2323692489 hasConcept C2908929049 @default.
- W2323692489 hasConcept C55493867 @default.
- W2323692489 hasConcept C71924100 @default.
- W2323692489 hasConcept C84393581 @default.
- W2323692489 hasConceptScore W2323692489C126322002 @default.
- W2323692489 hasConceptScore W2323692489C134018914 @default.
- W2323692489 hasConceptScore W2323692489C138976137 @default.
- W2323692489 hasConceptScore W2323692489C170493617 @default.
- W2323692489 hasConceptScore W2323692489C185592680 @default.
- W2323692489 hasConceptScore W2323692489C198710026 @default.
- W2323692489 hasConceptScore W2323692489C2775893369 @default.
- W2323692489 hasConceptScore W2323692489C2776533406 @default.
- W2323692489 hasConceptScore W2323692489C2776919658 @default.
- W2323692489 hasConceptScore W2323692489C2776970464 @default.
- W2323692489 hasConceptScore W2323692489C2777953023 @default.
- W2323692489 hasConceptScore W2323692489C2778163477 @default.
- W2323692489 hasConceptScore W2323692489C2778468042 @default.
- W2323692489 hasConceptScore W2323692489C2778913445 @default.
- W2323692489 hasConceptScore W2323692489C2780288358 @default.
- W2323692489 hasConceptScore W2323692489C2908929049 @default.
- W2323692489 hasConceptScore W2323692489C55493867 @default.
- W2323692489 hasConceptScore W2323692489C71924100 @default.
- W2323692489 hasConceptScore W2323692489C84393581 @default.
- W2323692489 hasIssue "Supplement 1" @default.
- W2323692489 hasLocation W23236924891 @default.
- W2323692489 hasLocation W23236924892 @default.
- W2323692489 hasOpenAccess W2323692489 @default.
- W2323692489 hasPrimaryLocation W23236924891 @default.
- W2323692489 hasRelatedWork W1975035453 @default.
- W2323692489 hasRelatedWork W1989160730 @default.
- W2323692489 hasRelatedWork W2016647631 @default.
- W2323692489 hasRelatedWork W2038571733 @default.
- W2323692489 hasRelatedWork W2077998387 @default.
- W2323692489 hasRelatedWork W2126797993 @default.
- W2323692489 hasRelatedWork W2133339247 @default.
- W2323692489 hasRelatedWork W2149410839 @default.
- W2323692489 hasRelatedWork W2190649397 @default.
- W2323692489 hasRelatedWork W2412177436 @default.
- W2323692489 hasVolume "30" @default.
- W2323692489 isParatext "false" @default.
- W2323692489 isRetracted "false" @default.
- W2323692489 magId "2323692489" @default.
- W2323692489 workType "article" @default.