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- W2323775923 abstract "The in vitro activity of cilofungin against 100 Candida species was compared with 5-flucytosine. amphotericin B and ketoconazole by two laboratories independently and in a blinded fashion using a macrotitre dilution broth method in saam-f medium. Cilofungin showed good in vitro activity against Candida albicans. Candida tropicalis and Candida glabrata (90% minimal inhibitory concentration [MIC] 3.2 μg/mL) but was inactive against other Candida species. When testing the susceptibility of cilofungin, 5-flucytosine and amphotericin B at the two centres, approximately 90% of the Candida strains had MICs differing by fourfold or less. However, when testing susceptibility of ketoconazole, only 51% of the Candida strains had MIC differences fourfold or less. MIC susceptibility testing with cilofungin, 5-flucytosine and amphotericin B in saam-f medium is reproducible." @default.
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- W2323775923 date "1992-01-01" @default.
- W2323775923 modified "2023-09-27" @default.
- W2323775923 title "Comparative Antifungal Activity of Cilofungin (LY121019) againstCandidaSpecies, Including Evaluation of Susceptibility Testing Method" @default.
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- W2323775923 doi "https://doi.org/10.1155/1992/260839" @default.
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